The LA Clippers (2-1) welcome the Portland Trail Blazers (1-3) to the Intuit Dome Wednesday. Tip is set for 10:30 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Trail Blazers vs. Clippers odds and make our expert NBA picks and predictions for the best bets.

Season series: First meeting; Clipers went 4-0 last season

The Clippers beat the Golden State Warriors 112-104 Sunday, closing as a 9-point road underdog. They have been an underdog in all 3 games this season and have covered in each. Their lone loss was a 116-113 home defeat to the Phoenix Suns to open the season. Los Angeles has been consistently efficient offensively, scoring at least 109 points in all 3 games. It is led by G James Harden, who is averaging 25 points per game (PPG).

The Trail Blazers have been the opposite of efficient offensively, scoring over 104 points just once in 4 games. They are coming off a 111-98 road loss to the Sacramento Kings Monday, pushing as a 13-point underdog. Portland is 2-1-1 against the spread (ATS) and 0-0-1 ATS on the road. It has allowed at least 111 points twice in 4 games. The Trail Blazers are led by G Jerami Grant, who is averaging 21.3 PPG.

Trail Blazers at Clippers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NBA odds. Lines last updated at 12:11 p.m. ET.

  • Moneyline (ML): Trail Blazers +280 (bet $100 to win $280) | Clippers -350 (bet $350 to win $100)
  • Against the spread (ATS): Trail Blazers +8.5 (-110) | Clippers -8.5 (-110)
  • Over/Under (O/U): 219.5 (O: -110 | U: -110)

Trail Blazers at Clippers key injuries

Trail Blazers

  • G Shaedon Sharpe (shoulder) out
  • F Matisse Thybulle (knee) out
  • C Robert Williams III (hamstring) out

Clippers

  • F Kawhi Leonard (knee) out
  • F P.J. Tucker (not with team) out

For most recent updates: Official NBA injury report.

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Trail Blazers at Clippers picks and predictions

Prediction

Clippers 116,  Trail Blazers 105

Moneyline

PASS.

The Clippers (-350)  should win this game, but they aren’t worthy a play as a strong home favorite. Similarly, the Trail Blazers have lost 3 of 4 and are 0-1 on the road. They aren’t worthy of a play as a sizable (+280) road underdog.

Against the spread

BET CLIPPERS -8.5 (-110).

The Clippers have been surging this season and have the star power in Harden to keep that up even without Leonard playing. Los Angeles has won all 3 games, including a pair against quality, playoff-caliber teams. Portland has lost 2 of its 4 games by double figures and is 0-1 ATS on the road.

The inefficiency in its stars, both of Portland’s top scorers have shot 42% from the field or worse, is worrisome and cause for concern. Take the more efficient side that has been exceeding expectations to start the season. Back CLIPPERS -8.5 (-110).

Over/Under

BET OVER 219.5 (-110).

The Trail Blazers are 2-2 O/U this season and have traded off going Over and Under in all 4 Games, primed to go Over in this one after putting up a mere 98 against the Kings Monday (they put up 125 on the Pelicans the Game prior).

The Clippers are 1-2 O/U, but have scored 109 or more in all 4 games, so they should be able to score more than their fair share of points. They have gone Over this total in 2 of 3 games and have hit at least 213 combined points in all 3.

Considering those trends, back OVER 219.5 (-110).

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