Inter Miami vs. Nashville SC prediction, odds: 2024 Concacaf Champions Cup picks, Messi best bets for March 13

A pair of familiar foes battle for a 2024 Concacaf Champions Cup quarterfinal berth on Wednesday as Inter Miami CF host Major League Soccer rival Nashville SC for the second leg of their Round of 16 tie. The two sides played to a 2-2 draw at Nashville in the first leg last week as Inter Miami allowed the first two goals before rallying in the second half. Both sides are 1-3-1 in their last five meetings across all competitions, with each of the last three encounters ending in a draw.

Kickoff at Chase Stadium in Fort Lauderdale, Fla., is set for 8:15 p.m. ET. Inter Miami are -215 favorites (risk $215 to win $100) in the latest Inter Miami vs. Nashville SC odds, while Nashville SC are +450 underdogs. A 90-minute draw is priced at +360 and the over/under for total goals scored is 2.5. Before locking in any Nashville SC vs. Inter Miami picks, you need to see what proven SportsLine soccer insider Jon "Buckets" Eimer has to say.

Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, he has covered the English Premier League, Serie A, the FA Cup and much more. In 2023, he was red-hot, going 248-234-12 for a profit of $2,593 for $100 bettors. That included an 86-59-5 record in the Premier League for a $3,463 profit.

Now, Eimer has broken down Inter Miami vs. Nashville SC from every angle and just revealed his picks and Concacaf Champions Cup predictions. You can head to SportsLine now to see Eimer's picks. Here are the betting lines and trends for Nashville SC vs. Inter Miami:

• Inter Miami vs. Nashville SC money line: Inter Miami -215, Nashville SC +450, Draw +360
• Inter Miami vs. Nashville SC over/under: 2.5 goals
• Inter Miami vs. Nashville SC spread: Inter Miami -1.5 (+135)
• IM: Have scored at least two goals in four of their last five matches across all competitions
• NASH: Are 2-4-0 across all competitions in 2024
• Inter Miami vs. Nashville SC picks: See picks at SportsLine

Why you should back Inter Miami 

The Herons made sure they would be at full strength for the second leg of this Round of 16 tie as Argentinian superstar Lionel Messi was rested on Sunday while Uruguayan striker Luis Suarez did not start and only saw 14 minutes of action in the team's 3-2 loss to CF Montreal. Both players were key in the first-leg draw as Suarez recorded a goal and an assist while Messi also converted. The 36-year-old Messi is tied for the MLS lead with three goals, as he scored in stoppage time to earn Inter Miami a 1-1 draw against the Los Angeles Galaxy and recorded a brace in their 5-0 triumph over Orlando City SC.

Suarez also converted twice against Orlando City and added a pair of assists, which gave him a league-leading three on the season. Finnish midfielder Robert Taylor is even with Suarez for second on the Herons with two goals, while midfielder Diego Gomez, forward Leonardo Campana and defender Jordi Alba also have scored in MLS play. See which team to pick here.

Why you should back Nashville SC

The Coyotes have received a solid effort in the Champions Cup thus far from Jacob Shaffelburg, who is third in the competition with three goals. The 24-year-old Canadian winger converted -- and notched an assist -- in Nashville's 4-0 triumph over Moca in the second leg of their Round One tie and netted both of the club's goals against Inter Miami last week. Shaffelburg has yet to score in three MLS matches this season and finished with three goals in 28 league games in 2022-23.

Forward Forster Ajago did not play versus the Herons in the first leg but recorded a brace in Nashville's second win against Moca. Striker Sam Surridge and midfielder Hany Mukhtar led the offense in the 3-0 first-leg triumph over the Dominican club as each registered a goal and an assist. Forward Teal Bunbury leads the Coyotes with two goals in MLS play, while English midfielder Dru Yearwood converted for the first time this season in Sunday's 2-2 draw with the Los Angeles Galaxy. See which team to pick here.

How to make Inter Miami vs. Nashville SC picks

Eimer has broken down Wednesday's match from every possible angle and is leaning Over on the total. He also has locked in a pair of confident best bets and is offering a full breakdown of this Champions Cup match. He's sharing his Champions Cup picks and analysis only at SportsLine.

So who wins Inter Miami vs. Nashville SC, and where does all the betting value lie? Visit SportsLine now to see which wagers in Nashville SC vs. Inter Miami have all the value, all from the soccer expert who had a profit of almost $2,600 in 2023, and find out.