We’ve tracked the most important line moves of Week 5 since Monday morning at BetMGM Sportsbook to see where the big money has been coming in and how injuries have been shaping the market.

One of the more dramatic line moves since Monday morning has been the New York Giants (1-3) being downgraded from 6- to 7-point underdogs at the Seattle Seahawks (3-1) Sunday. New York will be without rookie WR Malik Nabers (concussion), who leads Giants receivers with 386 yards and 3 TDs.

Arguably an equally important move has been the winless Jacksonville Jaguars (0-4) going from 2.5- to 3-point favorites over the visiting Indianapolis Colts (2-2). Indianapolis QB Anthony Richardson (oblique) is doubtful for Sunday, and the Colts will also be without RB Jonathan Taylor (ankle).

Coach Sean McVay and the LA Rams (1-3) have been upgraded from 3.5- to 3-point underdogs hosting his former offensive coordinator Matt LaFleur and the Green Bay Packers (2-2). Green Bay WR Romeo Doubs (suspension) is out, WR Christian Watson (ankle) is doubtful, and 2-time Pro Bowl CB Jaire Alexander (groin) is questionable.

The biggest shift in Week 5 totals has been the Baltimore Ravens (2-2) and Cincinnati Bengals (1-3) Over/Under moving 3 points from 51.5 to 48.5. Another notable adjustment has been the PackersRams total moving 2.5 points, going from 46.5 Monday morning to 49 at press time.

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Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 10:45 p.m. ET. — All Games Sunday and ET unless noted.

New York Jets vs. Minnesota Vikings, 9:30 a.m. (NFL Network)

East Rutherford, NJ -- September 29 -- His team mates pick up Aaron Rodgers of the Jets after he was sacked in the fourth quarter as the Denver Broncos edged the New York Jets 10-9 at MetLife Stadium.

New York Jets quarterback Aaron Rodgers (8) gets sacked against the Denver Broncos.

  • Current moneyline: Vikings -135 (Jets +115) | Opener: Vikings -150 (Jets +125)
  • Current spread: Vikings -2.5 (-110) | Opener: Vikings -2.5 (-115)
  • Current Over/Under: 40.5 | Opener: 40.5

Carolina Panthers at Chicago Bears, 1 p.m. (FOX)

  • Current moneyline: Bears -https://cdn.thefoxposts.com/vimedia/2024/10/07/9b4ef02a47a3ed28962a883c395da006.webp (Panthers +165) | Opener: Bears -https://cdn.thefoxposts.com/vimedia/2024/10/07/9b4ef02a47a3ed28962a883c395da006.webp (Panthers +165)
  • Current spread: Bears -4 (-110) | Opener: Bears -4 (-110)
  • Current Over/Under: 41 | Opener: 42.5

Baltimore Ravens at Cincinnati Bengals, 1 p.m. (CBS)

  • Current moneyline: Ravens -135 (Bengals +115) | Opener: Ravens -155 (Bengals +130)
  • Current spread: Ravens -2.5 (-110) | Opener: Ravens -2.5 (-115)
  • Current Over/Under: 48.5 | Opener: 51.5

Miami Dolphins at New England Patriots, 1 p.m. (FOX)

  • Current moneyline: Dolphins -115 (Patriots -105) | Opener: Dolphins -115 (Patriots -105)
  • Current spread: Dolphins -1 (-110) | Opener: Dolphins -1 (-110)
  • Current Over/Under: 35.5 | Opener: 36.5

Cleveland Browns at Washington Commanders, 1 p.m. (FOX)

Commanders quarterback Jayden Daniels (5) looks for open receivers against the Cardinals during a game at State Farm Stadium in Glendale on Sept. 29, 2024.

Washington CoMMAnders quarterback Jayden Daniels (5) in action against the Arizona Cardinals.

  • Current moneyline: Commanders -160 (Browns +135) | Opener: Commanders -165 (Browns +140)
  • Current spread: Commanders -3 (-110) | Opener: Commanders -3 (-115)
  • Current Over/Under: 43.5 | Opener: 44

Indianapolis Colts at Jacksonville Jaguars, 1 p.m. (CBS)

  • Current moneyline: Jaguars -165 (Colts +140) | Opener: Jaguars -145 (Colts +120)
  • Current spread: Jaguars -3 (-115) | Opener: Jaguars -2.5 (-120)
  • Current Over/Under: 45.5 | Opener: 46.5

Buffalo Bills at Houston Texans, 1 p.m. (CBS)

  • Current moneyline: Texans -120 (Bills +100) | Opener: Texans -120 (Bills +100)
  • Current spread: Texans -1 (-110) | Opener: Texans -1.5 (-110)
  • Current Over/Under: 47 | Opener: 46.5 (-115)

Las Vegas Raiders at Denver Broncos, 4:05 p.m. (FOX)

  • Current moneyline: Broncos -150 (Raiders +125) | Opener: Broncos -140 (Raiders +115)
  • Current spread: Broncos -3 (-105) | Opener: Broncos -2.5 (-105)
  • Current Over/Under: 35.5 | Opener: 37

Arizona Cardinals at San Francisco 49ers, 4:05 p.m. (FOX)

Sep 29, 2024; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) passes the football against the New England Patriots during the first quarter at Levi's Stadium. Mandatory Credit: Neville E. Guard-Imagn Images

San Francisco 49ers quarterback Brock Purdy (13) passes against the New England Patriots.

  • Current moneyline: 49ers -350 (Cardinals +280) | Opener: 49ers -375 (Cardinals +300)
  • Current spread: Cardinals +7 (-105) | Opener: Cardinals +7.5 (-110)
  • Current Over/Under: 49 | Opener: 50.5

Green Bay Packers at LA Rams, 4:25 p.m. (CBS)

  • Current moneyline: Packers -165 (Rams +140) | Opener: Packers -https://cdn.thefoxposts.com/vimedia/2024/10/07/9b4ef02a47a3ed28962a883c395da006.webp (Rams +165)
  • Current spread: Packers -3 (-115) | Opener: Packers -3.5 (-110)
  • Current Over/Under: 49 | Opener: 46.5

New York Giants at Seattle Seahawks, 4:25 p.m. (CBS)

  • Current moneyline: Seahawks -350 (Giants +275) | Opener: Seahawks -275 (Giants +230)
  • Current spread: Seahawks -7 (-110) | Opener: Seahawks -6 (-110)
  • Current Over/Under: 42.5 | Opener: 42

Dallas Cowboys at Pittsburgh Steelers, 8:20 p.m. (NBC)

  • Current moneyline: Steelers -145 (Cowboys +120) | Opener: Steelers -130 (Cowboys +110)
  • Current spread: Steelers -2.5 (-120) | Opener: Steelers -2.5 (-105)
  • Current Over/Under: 44 | Opener: 43

Monday: New Orleans Saints at Kansas City Chiefs, 8:15 p.m. (ESPN)

Sep 29, 2024; Atlanta, Georgia, USA; New Orleans Saints quarterback Derek Carr (4) passes the ball against the Atlanta Falcons during the second half at Mercedes-Benz Stadium. Mandatory Credit: Dale Zanine-Imagn Images

New Orleans Saints quarterback Derek Carr (4) in action against the Atlanta Falcons.

  • Current moneyline: Chiefs -250 (Saints +https://cdn.thefoxposts.com/vimedia/2024/10/07/9b4ef02a47a3ed28962a883c395da006.webp) | Opener: Chiefs -250 (Saints +https://cdn.thefoxposts.com/vimedia/2024/10/07/9b4ef02a47a3ed28962a883c395da006.webp)
  • Current spread: Chiefs -5.5 (-110) | Opener: Chiefs -6 (-110)
  • Current Over/Under: 43 | Opener: 42.5