You know it was a wild week in the NFL when even the Carolina Panthers (1-2) won a Game. They upset the Las Vegas Raiders (1-2), 36-22, as 5.5-point road underdogs Sunday. Underdogs have been profitable this season — 3 underdogs of 6-plus points won straight up in Week 3 — and we’ll see if that trend continues.
Week 4 kicks off with the New York Giants (1-2) — one of the big underdogs that won straight up in Week 3 — hosting the Dallas Cowboys (1-2) on Thursday Night Football. While they surprisingly have identical records, the Cowboys opened as 4.5-point road favorites coming off back-to-back home losses.
The party continues Sunday with the Philadelphia Eagles (2-1) Traveling to the Tampa Bay Buccaneers (2-1) for a rematch of an NFC Wild Card Game from last season. The Buccaneers beat Philadelphia 32-9 in the Jan. 15 playoff meeting as 3-point home underdogs. After losing to the Eagles in Week 3, the New Orleans Saints (2-1) look to take the lead over Tampa in the NFC South when they face the Atlanta Falcons (1-2) at Mercedes-Benz Stadium. Other noteworthy Games include the Minnesota Vikings (3-0) at the Green Bay Packers (2-1), the Pittsburgh Steelers (3-0) visiting the Indianapolis Colts (1-2), and the New York Jets (2-1) hosting the Denver Broncos (1-2).
Once the early games wrap up, QB Patrick Mahomes and the Kansas City Chiefs (3-0) will look to stay undefeated at the LA Chargers (2-1). The availability of QB Justin Herbert (ankle), though, has not been announced as of Monday. The afternoon also features the San Francisco 49ers (1-2) hosting the New England Patriots (1-2), the Cleveland Browns (1-2) visiting the Raiders, and the Washington Commanders (1-1 before MNF) at the Arizona Cardinals (1-2).
Sunday wraps up with 2 of the best QBs in the NFL facing off when Josh Allen and the Buffalo Bills (2-0 before MNF) visit Lamar Jackson and the Baltimore Ravens (1-2). A MNF doubleheader brings the week to a close with the Tennessee Titans (0-3) at the Miami Dolphins (1-2) while the Detroit Lions (2-1) look to hand the visiting Seattle Seahawks (3-0) their 1st loss.
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Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 11:13 a.m. ET. — All games Sunday and ET unless noted.
Thursday: Dallas Cowboys at New York Giants, 8:15 p.m. (Prime Video)
Dallas Cowboys quarterback Dak Prescott (4) during the fourth quarter against the Baltimore Ravens.
- Moneyline: Cowboys -225 (bet $100 to win $225) | Giants +185 (bet $100 to win $185)
- Against the spread: Cowboys -4.5 (-110) | Giants +4.5 (-110)
- Over/Under: 44 (O: -110 | U: -110)
New Orleans Saints at Atlanta Falcons, 1 p.m. (FOX)
- Moneyline: Saints +100 (bet $100 to win $100) | Falcons -120 (bet $120 to win $100)
- Against the spread: Saints +1.5 (-110) | Falcons -1.5 (-110)
- Over/Under: 43.5 (O: -110 | U: -110)
LA Rams at Chicago Bears, 1 p.m. (FOX)
- Moneyline: Rams +115 (bet $100 to win $115) | Bears -135 (bet $135 to win $100)
- Against the spread: Rams +2.5 (-110) | Bears -2.5 (-110)
- Over/Under: 41 (O: -110 | U: -110)
Minnesota Vikings at Green Bay Packers, 1 p.m. (CBS)
- Moneyline: Vikings +110 (bet $100 to win $110) | Packers -135 (bet $135 to win $100)
- Against the spread: Vikings +2.5 (-105) | Packers -2.5 (-115)
- Over/Under: 43.5 (O: -110 | U: -110)
Pittsburgh Steelers at Indianapolis Colts, 1 p.m. (CBS)
- Moneyline: Steelers -125 (bet $125 to win $100) | Colts +105 (bet $100 to win $105)
- Against the spread: Steelers -1.5 (-115) | Colts +1.5 (-105)
- Over/Under: 38.5 (O: -110 | U: -110)
Denver Broncos at New York Jets, 1 p.m. (CBS)
New York Jets quarterback Aaron Rodgers (8) pregame against the New England Patriots.
- Moneyline: Broncos +310 (bet $100 to win $310) | Jets -400 (bet $400 to win $100)
- Against the spread: Broncos +7.5 (-110) | Jets -7.5 (-110)
- Over/Under: 38.5 (O: -110 | U: -110)
Philadelphia Eagles at Tampa Bay Buccaneers, 1 p.m. (FOX)
- Moneyline: Eagles -145 (bet $145 to win $100) | Buccaneers +120 (bet $100 to win $120)
- Against the spread: Eagles -2.5 (-110) | Buccaneers +2.5 (-110)
- Over/Under: 45.5 (O: -105 | U: -115)
Cincinnati Bengals at Carolina Panthers, 1 p.m. (FOX)
- Moneyline: Bengals -250 (bet $250 to win $100) | Panthers +https://cdn.thefoxposts.com/vimedia/2024/09/24/27c98b1f9560bd856dc9f1d5d62ff588.webp (bet $100 to win $https://cdn.thefoxposts.com/vimedia/2024/09/24/27c98b1f9560bd856dc9f1d5d62ff588.webp)
- Against the spread: Bengals -5.5 (-110) | Panthers +5.5 (-110)
- Over/Under: 47.5 (O: -110 | U: -110)
Jacksonville Jaguars at Houston Texans, 1 p.m. (CBS)
- Moneyline: Jaguars +185 (bet $100 to win $185) | Texans -225 (bet $225 to win $100)
- Against the spread: Jaguars +4.5 (-110) | Texans -4.5 (-110)
- Over/Under: 45.5 (O: -110 | U: -110)
Washington Commanders at Arizona Cardinals, 4:05 p.m. (FOX)
- Moneyline: Commanders +190 (bet $100 to win $190) | Cardinals -225 (bet $225 to win $100)
- Against the spread: Commanders +5 (-110) | Cardinals -5 (-110)
- Over/Under: 49.5 (O: -110 | U: -110)
New England Patriots at San Francisco 49ers, 4:05 p.m. (FOX)
San Francisco 49ers quarterback Brock Purdy (13) reaches for a first down against the LA Rams.
- Moneyline: Patriots +450 (bet $100 to win $450) | 49ers -600 (bet $600 to win $100)
- Against the spread: Patriots +10.5 (-110) | 49ers -10.5 (-110)
- Over/Under: 40 (O: -110 | U: -110)
Cleveland Browns at Las Vegas Raiders, 4:25 p.m. (CBS)
- Moneyline: Browns -120 (bet $120 to win $100) | Raiders +100 (bet $100 to win $100)
- Against the spread: Browns -1.5 (+100) | Raiders +1.5 (-120)
- Over/Under: 37.5 (O: -110 | U: -110)
Kansas City Chiefs at LA Chargers, 4:25 p.m. (CBS)
- Moneyline: Chiefs -300 (bet $300 to win $100) | Chargers +240 (bet $100 to win $240)
- Against the spread: Chiefs -7 (-105) | Chargers +7 (-115)
- Over/Under: 39.5 (O: -110 | U: -110)
Buffalo Bills at Baltimore Ravens, 8:20 p.m. (NBC)
- Moneyline: Off the board
- Against the spread: Bills +2.5 (-110) | Ravens -2.5 (-110)
- Over/Under: 45.5 (O: -110 | U: -110)
Monday: Tennessee Titans at Miami Dolphins, 7:30 p.m. (ESPN)
- Moneyline: Titans -110 (bet $110 to win $100) | Dolphins -110 (bet $110 to win $100)
- Against the spread: Titans -1.5 (+100) | Dolphins +1.5 (-120)
- Over/Under: 37 (O: -110 | U: -110)
Monday: Seattle Seahawks at Detroit Lions, 8:15 p.m. (ABC/ESPN+)
Detroit Lions receiver Amon-Ra St. Brown (14) and quarterback Jared Goff (16) against the Arizona Cardinals.
- Moneyline: Seahawks +165 (bet $100 to win $165) | Lions -https://cdn.thefoxposts.com/vimedia/2024/09/24/27c98b1f9560bd856dc9f1d5d62ff588.webp (bet $https://cdn.thefoxposts.com/vimedia/2024/09/24/27c98b1f9560bd856dc9f1d5d62ff588.webp to win $100)
- Against the spread: Seahawks +4 (-110) | Lions -4 (-110)
- Over/Under: 47 (O: -110 | U: -110)
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