The San Antonio Spurs (6-6) welcome the Los Angeles Lakers (7-4) to Frost Bank Center Friday for NBA Cup group play. Tip is set for 7:30 p.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s NBA odds around the Lakers vs. Spurs odds and make our expert NBA picks and predictions for the best bets.

Season series: First meeting; Lakers won 2-1 last season

The Spurs beat the Washington Wizards 139-130 Wednesday, closing as a 9.5-point home favorite. They were led by F Victor Wembanyama, who scored 50 points and drilled 8 triples. San Antonio has won 3 of its last 4 games yet is just 2-4 against the spread (ATS) in its last 6 games. It is 6-6 ATS and 4-3 ATS at home.

The Lakers have rattled off 3 straight wins and beat the Memphis Grizzlies  128-123 at home Wednesday, closing as a 7.5-point favorite. They were led by F LeBron James, who had a triple-doube with 35 points, 12 rebounds and 14 assists. Los Angeles is 6-4 ATS, but just 1-4 ATS on the road.

Lakers at Spurs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NBA odds. Lines last updated at 12:38 a.m. ET.

  • Moneyline (ML): Lakers -150 (bet $150 to win $100) | Spurs +125 (bet $100 to win $125)
  • Against the spread (ATS): Lakers -3.5 (-105) | Spurs +3.5 (-115)
  • Over/Under (O/U): 225.5 (O: -115 | U: -105)

Lakers at Spurs key injuries

Lakers

  • F Anthony Davis (plantar) probable
  • G D’Angelo Russell (illness) probable
  • C Christian Wood (knee) out

Spurs

  • G Trey Jones (illness) out
  • F Jeremy Sochan (thumb) out

For most recent updates: Official NBA injury report.

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Lakers at Spurs picks and predictions

Prediction

Lakers 118, Spurs 116

Moneyline

PASS.

The Spurs have a good shot at winning this game outright, especially with how the Lakers are playing on the road. Given the spread here though, they are better played there.

Against the spread

BET SPURS +3.5 (-115).

The Lakers have won 3 in a row, and they have been nearly unbeatable at home. On the road, they have been a far different team. In their 5 away games, they are 1-4 straight up and ATS. Los Angeles has allowed 125 points or more in 3 of those road games.

The Spurs have scored at least 116 points in their last 2games and are 3-2 ATS at home in their last 5. They have scored well and should have the length in Wembanyama to limit Davis, the Lakers leading scorer. Considering those trends, back SPURS +3.5 (-115).

Over/Under

BET OVER 225.5 (-115).

The Lakers are 3-2 O/U on the road and have scored at least 116 points in 3 straight. Their top 2 scoring options, Davis and James, are shooting over 52% from the field. They have allowed 115 points or more in 4 of their 5 road games.

The Spurs are 6-6 O/U on the season and 5-2 O/U in their last seven. They have allowed at least 111 points in 3 of their last 5 games and averaged 127.5 points over their last 2. With that in mind, back OVER 225.5 (-115).

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