San Francisco 49ers vs New England Patriots Prediction 9-29-24 Picks

The New England Patriots and the San Francisco 49ers meet in week 4 NFL action from Levi’s Stadium on Sunday afternoon. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New England Patriots vs. San Francisco 49ers prediction.

New England Patriots Recap

The New England Patriots come into this one at 1-2 on the year after back-to-back losses following a 24-3 loss to the New York Jets last time out. After this Game, the Patriots will have their bye week before their division matchup against the Miami Dolphins.

Patriots Looking For Offense

Jacoby Brissett has thrown for 368 yards and a touchdown on 60.9% passing while Rhamondre Stevenson leads the Patriots on the ground with 224 rushing yards and 2 touchdowns. Antonio Gibson also has 143 rushing yards while Hunter Henry has a team-high 12 grabs for 136 yards this season. On defense, Jonathan Jones, Jahlani Tavai and Kyle Dugger each have a team-high 18 total tackles with Dugger logging a team-high 13 solo tackles. Keion White also has a team-high 4 sacks as well on the year for New England.

Why the New England Patriots will win

• The Patriots have won each of their last seven away games against opponents on a losing streak.
• The 49ers have lost four of their last five Sunday games as favorites.
• The 49ers have failed to cover the spread in eight of their last nine games in California.
• The underdogs have covered the spread in seven of the 49ers’ last eight games at Levi’s Stadium.

San Francisco 49ers Recap

The San Francisco 49ers come into this Game looking to rebound from back-to-back road losses after a 27-24 loss to the Los Angeles Rams in their last Game. After this Game, the 49ers will welcome the Arizona Cardinals to town for a divisional matchup.

49ers Trying To Rebound After Collapse

Brock Purdy has thrown for 842 yards, 4 touchdowns, and an interception on 72.6% passing while Jordan Mason’s rushed for 324 yards and 2 touchdowns on the year. Jauan Jennings has a team-high 18 receptions for 276 yards and 3 touchdowns while Deebo Samuel, Brandon Aiyuk, and George Kittle all have 100+ receiving yards as well for the 49ers this season. On defense, Fred Warner has a team-high 20 total tackles including 13 solo tackles and an interception while Nick Bosa has a pair of sacks. As a unit, San Francisco’s defense has combined for 8 sacks and a pair of interceptions so far this season.

Why the San Francisco 49ers will win

• The Patriots have lost each of their last seven games against teams that held a losing record.
• The 49ers have won each of their last six home games before a Division game.
• The Patriots have failed to cover the spread in each of their last seven Sunday games against teams that held a losing record.
• The 49ers have covered the spread in five of their last six home games against teams that held a losing record.

Patriots vs. 49ers Prediction

I’m on the under here. It’s a fairly low total, but I think it’s going to be important to keep an eye on the 49ers injury report throughout the week to see if guys like Kittle and Deebo come back. I’m still not giving any love to this Patriots’ offense as it’s been frankly non-existent and lackluster to put it nicely and I think the 49ers want to just suffocate the Patriots with their defense. It’s a fairly low total, but I don’t envision a ton of scoring here. Give me the under.