The San Diego Padres (83-65) face the San Francisco Giants (72-76) in the 2nd game of their 3-game series Saturday. First pitch from Oracle Park is at 9:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 6-5.

The Padres won the opener Friday night 5-0 and retook the Wild Card lead over the Arizona Diamondbacks by a half game. They are 6-4 in  their last 10 games.

The Giants were shut out for the 2nd straight game Friday and have lost 3 of their last 4 games. They are 4-8 in their last 12 games.

Padres at Giants projected starters

RHP Joe Musgrove vs. RHP Mason Black

Musgrove (5-5, 4.54 ERA) makes his 17th start. He has a 1.28 WHIP, 2.4 BB/9 and 8.6 K/9 through 81 1/3 innings.

  • Last start: Loss, 4 1/3 IP, 6 ER, 8 H, 1 BB, 7 K in 7-6 home loss to the Giants Sunday
  • Had allowed only 4 ER in previous 5 starts combined
  • 4-5 with 4.46 ERA in 15 career starts vs. Giants

Black (0-3, 7.50 ERA) makes his 6th start and 7th appearance. He has a 1.63 WHIP, 3.0 BB/9 and 8.3 K/9 through 24 innings.

  • Last start: Loss, 4 2/3 IP, 4 ER, 6 H, 1 BB, 6 K in 5-1 road loss to the Padres last Friday, his only career game against the them
  • Has allowed 4+ ER in 3 of 5 starts

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Padres at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 12:40 p.m. ET.

  • Moneyline (ML): Padres -160 (bet $160 to win $100) | Giants +135 (bet $100 to win $135)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+105) | Giants +1.5 (-125)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

Padres at Giants picks and predictions

Prediction

Padres 5, Giants 2

Moneyline

The Giants have scored 2 or fewer runs in their last 4 losses. They beat Musgrove last week, but Black has not been great thus far,

Musgrove got lit up for 6 runs in his last start, but his ERA was 1.16 in his previous 4.

He will bounce back, but the run line is the better bet for the Padres.

PASS. 

Run line/Against the spread

Seven of the Padres’ last 9 wins have been by more than 1 run. All 5 of their wins over the Giants this season have been by 2+ runs.

Seven of the Giants’ last 10 losses have been my multiple runs.

BET PADRES -1.5 (+105). 

Over/Under

Six of the 11 games they have played against each other this season have had 8 or more runs.

The Giants’ last 4 losses have not reached 8 total runs.

Six of the Padres’ last 10 games have not reached 8 total runs.

BET UNDER 7.5 (-105). 

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