QB Patrick Mahomes and the Kansas City Chiefs had to pull off upsets in 3 straight playoff games to win their 2nd straight Super Bowl last season. They kick off this season Thursday hosting QB Lamar Jackson and the Baltimore Ravens — the team Kansas City beat in the AFC Championship game. The Chiefs (+500 at BetMGM Sportsbook) and Ravens (+1000) own the 1st- and 3rd-shortest odds, respectively, to win outright this season.

Twitter/X may be suspended in Brazil, but the NFL’s South American debut will still have social media buzzing, as the Green Bay Packers take on the Philadelphia Eagles in Sau Paulo Friday. QB Jalen Hurts’ Eagles are the 3rd-favorite to win the NFC (+550), while Jordan Love’s side has the 4th-shortest odds (+750).

The Chicago Bears selected QB Caleb Williams out of USC with the 1st overall pick in the NFL Draft, and their Over/Under of 8.5 wins (Over: -165 | Under: +140) reflects the team’s heightened expectations. Chicago hosts the Tennessee Titans Sunday in a 1 p.m. ET slate which features multiple QBs making their team debuts. Russell Wilson will try to lead the Pittsburgh Steelers in an upset over Kirk Cousins and the Atlanta Falcons at Mercedes-Benz Stadium, and Sam Darnold returns to MetLife Stadium with the Minnesota Vikings to face the New York Giants.

LA Chargers coach Jim Harbaugh (the favorite to win COTY at +900) will look to get QB Justin Herbert back on the winning track as they open the season hosting the Las Vegas Raiders in the afternoon slate. If preseason results are predictive of the regular season, then the Seattle Seahawks may be in trouble when they host Denver Broncos coach Sean Payton and QB Bo Nix. Washington Commanders rookie QB Jayden Daniels makes his debut at the Tampa Bay Buccaneers, and QB Dak Prescott and the Dallas Cowboys open as underdogs at the Cleveland Browns.

The Sunday slate wraps up with a rematch of a Wild Card Game from last season — the LA Rams at the Detroit Lions — and QB Aaron Rodgers returns from an Achilles injury as the New York Jets visit the San Francisco 49ers, who lost to the Chiefs in Super Bowl LVIII, on Monday Night Football.

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Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 10:55 a.m. ET. — All games Sunday and ET unless noted.

TNF: Baltimore Ravens at Kansas City Chiefs, 8:20 p.m. (NBC/Peacock)

Kansas City Chiefs quarterback Patrick Mahomes (15) reacts to play against the Chicago Bears.

Kansas City Chiefs quarterback Patrick Mahomes (center) reacts to play against the Chicago Bears during an NFL preseason game at Arrowhead Stadium. Photo: Denny Medley-USA TODAY Sports

  • Moneyline: Ravens +130 (bet $100 to win $130) | Chiefs -155 (bet $155 to win $100)
  • Against the spread: Ravens +3 (-115) | Chiefs -3 (-105)
  • Over/Under: 46.5 (O: -110 | U: -110)

Friday: Gren Bay Packers vs. Philadelphia Eagles, 8:15 p.m. (Peacock)

Green Bay Packers quarterback Jordan Love (10) runs through a drill.

Green Bay Packers quarterback Jordan Love (10) runs through a drill during a joint practice with the Baltimore Ravens at Ray Nitschke Field in Ashwaubenon, Wis. Tork Mason/USA TODAY NETWORK-Wisconsin

  • Moneyline: Packers +125 (bet $100 to win $125) | Eagles -150 (bet $150 to win $100)
  • Against the spread: Packers +3 (-125) | Eagles -3 (-105)
  • Over/Under: 48.5 (O: -110 | U: -110)

Jacksonville Jaguars at Miami Dolphins, 1 p.m. (CBS)

Miami Dolphins quarterback Tua Tagovailoa (1) against the Washington Commanders.

Miami Dolphins quarterback Tua Tagovailoa (1) after a pass against the Washington CoMMAnders during the first quarter of a preseason Game at Hard Rock Stadium. Mandatory Credit: Sam Navarro-USA TODAY Sports

  • Moneyline: Jaguars +135 (bet $100 to win $135) | Dolphins -165 (bet $165 to win $100)
  • Against the spread: Jaguars +3 (-105) | Dolphins -3 (-115)
  • Over/Under: 49.5 (O: -110 | U: -110)

Pittsburgh Steelers at Atlanta Falcons, 1 p.m. (FOX)

  • Moneyline: Steelers +130 (bet $100 to win $130) | Falcons -155 (bet $155 to win $100)
  • Against the spread: Steelers +3 (-115) | Falcons -3 (-105)
  • Over/Under: 42.5 (O: -110 | U: -110)

Minnesota Vikings at New York Giants, 1 p.m. (FOX)

  • Moneyline: Vikings -120 (bet $120 to win $100) | Giants +100 (bet $100 to win $100)
  • Against the spread: Vikings -1 (-110) | Giants +1 (-110)
  • Over/Under: 41.5 (O: -110 | U: -110)

Carolina Panthers at New Orleans Saints, 1 p.m. (FOX)

  • Moneyline: Panthers +175 (bet $100 to win $175) | Saints -210 (bet $210 to win $100)
  • Against the spread: Panthers +4.5 (-120) | Saints -4.5 (+100)
  • Over/Under: 41.5 (O: -110 | U: -110)

New England Patriots at Cincinnati Bengals, 1 p.m. (CBS)

  • Moneyline: Patriots +325 (bet $100 to win $325) | Bengals -400 (bet $400 to win $100)
  • Against the spread: Patriots +8.5 (-105) | Bengals -8.5 (-115)
  • Over/Under: 40.5 (O: -110 | U: -110)

Tennessee Titans at Chicago Bears, 1 p.m. (FOX)

Chicago Bears quarterback Caleb Williams (18) talks with media on the sidelines against the Kansas City Chiefs during the second half at GEHA Field at Arrowhead Stadium. Mandatory Credit: Denny Medley-USA TODAY Sports

  • Moneyline: Titans +170 (bet $100 to win $170) | Bears -210 (bet $210 to win $100)
  • Against the spread: Titans +4.5 (-110) | Bears -4.5 (-110)
  • Over/Under: 45.5 (O: -110 | U: -110)

Arizona Cardinals at Buffalo Bills, 1 p.m. (CBS)

  • Moneyline: Cardinals +225 (bet $100 to win $225) | Bills -275 (bet $275 to win $100)
  • Against the spread: Cardinals +6 (-110) | Bills -6 (-110)
  • Over/Under: 48 (O: -115 | U: -105)

Houston Texans at Indianapolis Colts, 1 p.m. (CBS)

  • Moneyline: Texans -150 (bet $150 to win $100) | Colts +125 (bet $100 to win $125)
  • Against the spread: Texans -2.5 (-110) | Colts +2.5 (-110)
  • Over/Under: 48.5 (O: -115 | U: -105)

Las Vegas Raiders at LA Chargers, 4:05 p.m. (CBS)

  • Moneyline: Raiders +145 (bet $100 to win $145) | Chargers -175 (bet $175 to win $100)
  • Against the spread: Raiders +3.5 (-115) | Chargers -3.5 (-105)
  • Over/Under: 41.5 (O: -110 | U: -110)

Denver Broncos at Seattle Seahawks, 4:05 p.m. (CBS)

Denver Broncos quarterback Bo Nix warms up in the first quarter against the Green Bay Packers at Empower Field at Mile High. Mandatory Credit: Ron Chenoy-USA TODAY Sports

  • Moneyline: Broncos +https://cdn.thefoxposts.com/vimedia/2024/09/03/46478e0dc88a1090c31462c6bb1b6b55.webp (bet $100 to win $https://cdn.thefoxposts.com/vimedia/2024/09/03/46478e0dc88a1090c31462c6bb1b6b55.webp) | Seahawks -250 (bet $250 to win $100)
  • Against the spread: Broncos +5.5 (-110) | Seahawks -5.5 (-110)
  • Over/Under: 42 (O: -110 | U: -110)

Washington Commanders at Tampa Bay Buccaneers, 4:05 p.m. (FOX)

  • Moneyline: Commanders +150 (bet $100 to win $150) | Buccaneers -185 (bet $185 to win $100)
  • Against the spread: Commanders +3.5 (-115) | Buccaneers -3.5 (-105)
  • Over/Under: 43.5 (O: -110 | U: -110)

Dallas Cowboys at Cleveland Browns, 4:25 p.m. (FOX)

  • Moneyline: Cowboys +120 (bet $100 to win $120) | Browns -145 (bet $145 to win $100)
  • Against the spread: Cowboys +2.5 (-105) | Browns -2.5 (-115)
  • Over/Under: 42.5 (O: -110 | U: -110)

LA Rams at Detroit Lions, 8:20 p.m. (NBC/Peacock)

Los Angeles Rams quarterbacks Dresser Winn (4), Matthew Stafford (9), Stetson Bennett (13) and Jimmy Garoppolo (11) walk onto the field before the game against the Houston Texans at NRG Stadium. Mandatory Credit: Troy Taormina-USA TODAY Sports

  • Moneyline: Rams +150 (bet $100 to win $150) | Lions -185 (bet $185 to win $100)
  • Against the spread: Rams +3.5 (-115) | Lions -3.5 (-105)
  • Over/Under: 51 (O: -110 | U: -110)

MNF: New York Jets at San Francisco 49ers, 8:20 p.m. (ESPN/ABC/ESPN+)

New York Jets quarterback Aaron Rodgers (left) and New York Giants quarterback Daniel Jones talk following the game at MetLife Stadium. Mandatory Credit: Rich Barnes-USA TODAY Sports

  • Moneyline: Jets +165 (bet $100 to win $165) | 49ers -https://cdn.thefoxposts.com/vimedia/2024/09/03/46478e0dc88a1090c31462c6bb1b6b55.webp (bet $https://cdn.thefoxposts.com/vimedia/2024/09/03/46478e0dc88a1090c31462c6bb1b6b55.webp to win $100)
  • Against the spread: Jets +3.5 (-110) | 49ers -3.5 (-110)
  • Over/Under: 43.5 (O: -115 | U: -105)

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