College Football Week 2 opening lines, odds and best bet | Pickswise

Week 1 of the college Football season is almost in the books. It was an exciting week of action and there were plenty of eye-opening results. Miami took care of Business against Florida at the Swamp. Notre Dame went into Kyle Field and defeated Texas A&M. Penn State’s offense looked crisp in its win at West Virginia, unlike Clemson’s offense – which didn’t score a touchdown in its 34-3 loss to Georgia. As we turn the page on Week 1, it’s time to look forward to Week 2 and a fresh slate of Games and lines for the first time in months. Let’s take a look at some of the biggest college Football Week 2 matchups with the latest odds and lines, and cap it off with a college Football best bet to make right now.

College Football Week 2 opening odds and lines

Odds courtesy of Caesars Sportsbook and available at time of publishing.

• Arkansas vs Oklahoma State (-10)
• Kansas State (-10.5) vs Tulane
• Pitt vs Cincinnati (-2.5)
• Troy vs Memphis (-17)
• Georgia Tech (-2) vs Syracuse 
• Texas (-5.5) vs Michigan
• Iowa State vs Iowa (-3)
• Cal vs Auburn (-11)
• Charlotte vs North Carolina (-23)
• Michigan State vs Maryland (-8.5)
• Baylor vs Utah (-16.5)
• South Carolina vs Kentucky (-8.5)
• Marshall vs Virginia Tech (-17)
• East Carolina vs Old Dominion (-1.5)
• Virginia vs Wake Forest (-2.5)
• San Jose State vs Air Force (-4.5)
• USF vs Alabama (-31)
• Colorado vs Nebraska (-6.5)
• Tennessee (-7.5) vs NC State 
• Houston vs Oklahoma (-27.5)
• App State vs Clemson (-16)
• Texas Tech vs Washington State (PK)
• Boise State vs Oregon (-20)
• Oregon State (-6) vs San Diego State
• Mississippi State vs Arizona State (-3.5)

If you’re looking to place a bet on college Football this week, then we recommend using Caesars Sportsbook. Not only do they offer some of the best odds available, but right now new users can sign up by clicking here and receive up to $1,000 in first-bet insurance!

College Football Week 2 best bet: Nebraska Cornhuskers -6.5 (-110) over Colorado Buffaloes

Colorado’s season began with a Friday night thriller at home in which they narrowly escaped with a victory over North Dakota State. The Buffaloes struggled to contain the Bison offense, yielding 449 total yards and losing the time-of-possession battle by more than 13 minutes. However, Colorado’s offense looked extremely potent against their FCS opponent, accumulating over 500 yards of total offense – 445 of which came through the air. It won’t be as easy for the Buffaloes in Week 2, though. Nebraska was top 15 in total defense and scoring defense in the FBS last season, and the Cornhuskers returned 70% of their production on that side of the ball, including top corner Tommi Hill. 

Nebraska’s offense is led by true freshman quarterback Dylan Raiola, who looked good against UTEP in Week 1. The freshman passed the ball 36 times, completing 25 of those attempts with 238 yards, 2 touchdowns and no interceptions. This is a big step up in class for Raiola, but he will benefit from this Game being at home in front of the Nebraska faithful. It also helps to be playing against a defense like Colorado’s, which did not seem to be vastly improved from last season in its win over North Dakota State in Week 1. After a slight adjustment of Colorado in my power ratings, I have this Game around -8 for Nebraska and would recommend a play on the Cornhuskers at -7 or better.

You can find out our college Football picks for all the big matchups throughout the season!