College Football Week 13 opening lines, odds and best bet | Pickswise

College Football Week 13 is here, which means this is the penultimate week of the regular season. With just 2 weeks remaining, we have only 2 more opportunities to cash-in on early week lines and odds. Tulane cashed with ease for us last week, improving our record to 8-3 on these opening line best bets – a win rate of 72.7%. Let’s get right into it, and make sure you check Pickswise daily for college Football picks and CFB predictions on all the biggest Games this week and for the rest of the season. 

College football Week 13 opening lines and odds

Odds courtesy of Bet365 at the time of publishing on Sunday evening.

• Miami (OH) -2.5 (-110) vs Northern Illinois – Tuesday, November 19th
• Toledo -2.5 (-110) vs Ohio – Wednesday, November 20th
• Georgia Tech -9 (-110) vs NC State – Thursday, November 21st
• UNLV -7.5 (-105) @ San Jose State – Friday, November 22nd
• Rutgers -2 (-110) vs Illinois – Saturday, November 23rd
• Ohio State -11.5 (-110) vs Indiana – Saturday, November 23rd
• Iowa -6 (-110) @ Maryland – Saturday, November 23rd
• Ole Miss -9.5 (-110) @ Florida – Saturday, November 23rd
• Jacksonville State -6 (-110) vs Sam Houston State – Saturday, November 23rd
• SMU -9.5 (-110) @ Virginia – Saturday, November 23rd
• Miami -24 (-110) vs Wake Forest – Saturday, November 23rd
• Western Kentucky -1 (-110) @ Liberty – Saturday, November 23rd
• Bowling Green -11.5 (-110) @ Ball State – Saturday, November 23rd
• James Madison -7 (-110) @ Appalachian State – Saturday, November 23rd
• Arizona State -3.5 (-110) vs BYU – Saturday, November 23rd
• UCF -3 (-110) @ West Virginia – Saturday, November 23rd
• Colorado -2.5 (-110) @ Kansas – Saturday, November 23rd
• Texas -20.5 (-110) vs Kentucky – Saturday, November 23rd
• Michigan -12 (-110) vs Northwestern – Saturday, November 23rd
• Penn State -12 (-110) @ Minnesota – Saturday, November 23rd
• Texas Tech -3.5 (-110) @ Oklahoma State – Saturday, November 23rd
• Nebraska -2.5 (-110) vs Wisconsin – Saturday, November 23rd
• Missouri -7.5 (-110) @ Mississippi State – Saturday, November 23rd
• Louisiana -11.5 (-110) vs Troy – Saturday, November 23rd
• Baylor -8 (-110) @ Houston – Saturday, November 23rd
• Boise State -22.5 (-110) @ Wyoming – Saturday, November 23rd
• Washington State -13.5 (-110) @ Oregon State – Saturday, November 23rd
• Alabama -14 (-110) @ Oklahoma – Saturday, November 23rd
• Notre Dame -16.5 (-110) vs Army – Saturday, November 23rd
• Iowa State -6 (-110) @ Utah – Saturday, November 23rd
• Old Dominion -2 (-110) vs Marshall – Saturday, November 23rd
• Texas A&M -2.5 (-110) @ Auburn – Saturday, November 23rd
• LSU -9 (-110) vs Vanderbilt – Saturday, November 23rd
• Kansas State -8.5 (-110) vs Cincinnati – Saturday, November 23rd
• USC -5 (-110) @ UCLA – Saturday, November 23rd

CFB Week 13 opening line best bet: Arizona State Sun Devils -3.5 over BYU Cougars (-110)

The Sun Devils and the Cougars experienced much different results in Week 12. The former won at Kansas State, while the latter lost at home to Kansas. With the loss, BYU dropped into a 2-way tie with Colorado atop the Big 12 standings. Meanwhile, Arizona State rose into a tie for 2nd with Iowa State in the conference standings with its win over the Jayhawks. If the Sun Devils manage to pull out the victory at home against BYU this week, they put themselves in a very good position to earn a Big 12 Championship Game berth with their final game being against in-state rival Arizona – who is 4-6 overall and 2-5 in conference.. 

Arizona State is set up for success against this BYU defense. The Sun Devils have kept the ball on the ground at a top 25 rate since Week 7, spearheaded by running back Cam Skattebo and his 1,074 rushing yards and 11 touchdowns. Skattebo is graded the 2nd-best runner in the Big 12 by PFF, as he has the 2nd-most yards after contact and missed tackles forced in the Big 12 despite missing a conference Game. BYU will counter with a defense that is 89th in opposing rush PPA, 95th in rush success rate and 84th in rush explosiveness outside of garbage time since Week 7. The Cougars also struggle to finish drives defensively, as they are 111th in opposing red zone scoring rate this season and 113th in opposing points per scoring opportunity in the last 6 weeks. This is a very difficult spot situationally for BYU following its first loss of the season, playing on the road against an Arizona State team that has won every home Game by at least 4.