49ers vs. Buccaneers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 3:17 p.m..

  • Moneyline (ML): San Francisco -275 (Bet $275 to win $100) | Tampa Bay +220 (Bet $100 to win $220)
  • Against the spread (ATS): San Francisco -6 (-110) | Tampa Bay +6 (-110)
  • Over/Under (O/U): 50.5 (O: -110 | U: -110)

49ers vs. Buccaneers betting tips preview

Best bets are available as the Tampa Bay Buccaneers (4-5) head into a matchup against the San Francisco 49ers (4-4) on Sunday, November 10, 2024 at Raymond James Stadium on a three-Game losing streak.

The most recent outing for the 49ers was a matchup with the Dallas Cowboys, and they emerged victorious 30-24. The Buccaneers lost by a final score of 30-24 last time out against the Chiefs. In that last outing for the 49ers, Brock Purdy completed 18 of 26 passing attempts (69.2%) and totaled 260 yards through the air, connecting on one touchdown pass and one touchdown as a rusher. Isaac Guerendo had 14 rushing attempts and wound up with 85 yards and one touchdown. George Kittle found paydirt once, and ended the contest with six catches for 128 yards.

In the Buccaneers’ last Game, Baker Mayfield threw for 200 yards on 23-31 passing (74.2%), adding two touchdowns. Bucky Irving ran for 24 yards on seven attempts. Cade Otton earned 77 yards on eight receptions with one score.

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49ers vs. Buccaneers key injuries

49ers

  • DL Nick Bosa (hip) limited participation in practice
  • WR Chris Conley (hamstring) did not participate in practice
  • OL Jon Feliciano (knee) limited participation in practice
  • DL Kevin Givens (groin) did not participate in practice
  • CB Renardo Green (ankle) full participation in practice
  • DL Yetur Gross-Matos (knee) limited participation in practice
  • WR Jauan Jennings (hip) limited participation in practice
  • RB Jordan Mason (shoulder) full participation in practice
  • RB Christian McCaffrey (achilles) limited participation in practice
  • K Jake Moody (ankle) limited participation in practice
  • WR Deebo Samuel (oblique) limited participation in practice
  • CB Charvarius Ward (personal) did not participate in practice
  • OT Trent Williams (rest) did not participate in practice
  • LB Dee Winters (concussion) full participation in practice
  • P Mitch Wishnowsky (back) limited participation in practice

Buccaneers

  • OG Ben Bredeson (shoulder) limited participation in practice
  • LS Evan Deckers (hamstring) full participation in practice
  • WR Mike Evans (hamstring) did not participate in practice
  • DL Greg Gaines (calf) limited participation in practice
  • DL William Gholston (knee) limited participation in practice
  • RB Bucky Irving (toe) limited participation in practice
  • QB Baker Mayfield (toe) did not participate in practice
  • WR Jalen McMillan (hamstring) did not participate in practice
  • LB JJ Russell (ribs) limited participation in practice
  • WR Sterling Shepard (hamstring) did not participate in practice
  • NT Vita Vea (hip) limited participation in practice
  • S Jordan Whitehead (quad) did not participate in practice

Prediction

Buccaneers 31, 49ers 21

Moneyline

  • Moneyline pick: Buccaneers +220
  • The 49ers have an implied moneyline win probability of 73.3% in this game.
  • San Francisco has compiled a 4-4 record in games they were favored on the moneyline (winning 50% of those games).
  • When playing as a moneyline favorite with odds of -275 or shorter, the 49ers have a 1-2 record (winning just 33.3% of their games).
  • Tampa Bay has won two of the six games it has played as an underdog this season.
  • This season, the Buccaneers have won one of their two games when they’re the underdog by at least +220 on the moneyline.

Against the spread

  • Pick ATS: Buccaneers (+6)
  • San Francisco has gone 4-4-0 ATS this season.
  • The 49ers have covered the spread once this season when favored by 6 points or more (in three chances).
  • Tampa Bay owns a record of 5-4-0 against the spread this season.
  • The Buccaneers have always covered the spread this year when underdogs by 6 points or more.

Over/under

  • Pick OU: Over (50.5)
  • The Buccaneers have played six games this season that finished with a point total above 50.5 points.
  • The teams combine to score 55.1 points per game, 4.6 more points than this matchup’s over/under.
  • Opponents of these two teams combine to score 49.8 points per game, 0.7 fewer points than this contest’s total.

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