The Detroit Lions versus the Houston Texans is a Game to watch on a Week 10 NFL Sunday slate that has plenty of exciting matchups.
Here is the betting info to break down ahead of Week 10 in the NFL.
Watch the NFL on Fubo!Today’s betting odds and lines
NFL odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 5:59 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
New York Giants at Carolina Panthers
- Game time: 9:30 a.m. ET
- Game location: Allianz Arena in Munich, Germany
- Spread favorite: Giants (-6.5)
- Over/under: 40.5 points
- Moneyline odds: Giants (-294) | Panthers (+236)
- TV channel: NFL Network
- Live stream: Watch on Fubo
Buffalo Bills at Indianapolis Colts
- Game time: 1 p.m. ET
- Game location: Lucas Oil Stadium in Indianapolis, Indiana
- Spread favorite: Bills (-4.5)
- Over/under: 46.5 points
- Moneyline odds: Bills (-228) | Colts (+187)
- TV channel: CBS
- Live stream: Fubo | Paramount+
Atlanta Falcons at New Orleans Saints
- Game time: 1 p.m. ET
- Game location: Caesars Superdome in New Orleans, Louisiana
- Spread favorite: Falcons (-3.5)
- Over/under: 47.5 points
- Moneyline odds: Falcons (-193) | Saints (+161)
- TV channel: FOX
- Live stream: Watch on Fubo
Minnesota Vikings at Jacksonville Jaguars
- Game time: 1 p.m. ET
- Game location: EverBank Stadium in Jacksonville, Florida
- Spread favorite: Vikings (-7)
- Over/under: 42.5 points
- Moneyline odds: Vikings (-331) | Jaguars (+265)
- TV channel: FOX
- Live stream: Watch on Fubo
Denver Broncos at Kansas City Chiefs
- Game time: 1 p.m. ET
- Game location: GEHA Field at Arrowhead Stadium in Kansas City, Missouri
- Spread favorite: Chiefs (-7.5)
- Over/under: 42.5 points
- Moneyline odds: Chiefs (-364) | Broncos (+283)
- TV channel: CBS
- Live stream: Fubo | Paramount+
New England Patriots at Chicago Bears
- Game time: 1 p.m. ET
- Game location: Soldier Field in Chicago, Illinois
- Spread favorite: Bears (-6.5)
- Over/under: 37.5 points
- Moneyline odds: Bears (-299) | Patriots (+241)
- TV channel: FOX
- Live stream: Watch on Fubo
Pittsburgh Steelers at Washington Commanders
- Game time: 1 p.m. ET
- Game location: Commanders Field in Landover, Maryland
- Spread favorite: Commanders (-1.5)
- Over/under: 45 points
- Moneyline odds: Commanders (-125) | Steelers (+105)
- TV channel: CBS
- Live stream: Fubo | Paramount+
San Francisco 49ers at Tampa Bay Buccaneers
- Game time: 1 p.m. ET
- Game location: Raymond James Stadium in Tampa, Florida
- Spread favorite: 49ers (-6.5)
- Over/under: 50.5 points
- Moneyline odds: 49ers (-293) | Buccaneers (+236)
- TV channel: FOX
- Live stream: Watch on Fubo
Tennessee Titans at Los Angeles Chargers
- Game time: 4:05 p.m. ET
- Game location: SoFi Stadium in Inglewood, California
- Spread favorite: Chargers (-8)
- Over/under: 39.5 points
- Moneyline odds: Chargers (-400) | Titans (+312)
- TV channel: FOX
- Live stream: Watch on Fubo
New York Jets at Arizona Cardinals
- Game time: 4:25 p.m. ET
- Game location: State Farm Stadium in Glendale, Arizona
- Spread favorite: Jets (-1.5)
- Over/under: 45.5 points
- Moneyline odds: Jets (-130) | Cardinals (+110)
- TV channel: CBS
- Live stream: Fubo | Paramount+
Philadelphia Eagles at Dallas Cowboys
- Game time: 4:25 p.m. ET
- Game location: AT&T Stadium in Arlington, Texas
- Spread favorite: Eagles (-7)
- Over/under: 44 points
- Moneyline odds: Eagles (-355) | Cowboys (+282)
- TV channel: CBS
- Live stream: Fubo | Paramount+
Detroit Lions at Houston Texans
- Game time: 8:20 p.m. ET
- Game location: NRG Stadium in Houston, Texas
- Spread favorite: Lions (-3.5)
- Over/under: 49.5 points
- Moneyline odds: Lions (-187) | Texans (+156)
- TV channel: NBC
- Live stream: Fubo | Peacock
