Our computer prediction projects a relatively comfortable win (28-19) for the Green Bay Packers (7-3) over the San Francisco 49ers (5-5) on Sunday, Nov. 24 at Lambeau Field (kickoff at 4:25 p.m. ET).

Packers vs. 49ers predictions

  • Pick ATS: Packers (-5.5)
  • Pick OU: Over (44.5)
  • Prediction:
    Packers 28 – 49ers 19

Packers vs. 49ers odds and lines

National Football League odds courtesy of BetMGM. Odds updated Sunday at 11:36 a.m. ET. For a full list of Sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Spread favorite: Packers (-5.5)
  • Moneyline: Packers (-250), 49ers (+200)
  • Total: 44.5 points

Packers betting stats

  • Against the spread, Green Bay is 4-6-0 this season.
  • As a 5.5-point favorite or greater, the Packers have one win ATS (1-1) this season.
  • Out of 10 Green Bay games so far this season, four have hit the over.

49ers betting stats

  • Against the spread, San Francisco is 4-6-0 this year.
  • Of 10 San Francisco games so far this year, five have hit the over.
  • The 49ers have not played a game this season while listed as the underdog.

Packers vs. 49ers game info

  • Game day: Sunday, November 24, 2024
  • Game time: 4:25 p.m. ET
  • TV channel: FOX
  • Location: Green Bay, Wisconsin
  • Stadium: Lambeau Field
  • TV channel: FOX
  • Live stream: Watch Redzone & other NFL content all season long on Fubo
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