The Minnesota Twins (51-39) and Chicago White Sox (26-66) open a 3-game set Monday. First pitch from Guaranteed Rate Fied is at 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Twins vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Twins lead 7-0

The Twins have won their last 5 series and are 10-4 in their last 14 games. They won the final 2 games of their series at home against the Houston Astros and are coming off a 3-2 win Sunday with the Under (9) cashing in.

The White Sox have lost 2 in a row and are coming off a 7-4 road loss to the Miami Marlins Sunday. They are 5-5 in their last 10 games after going 7-30 before that.

Twins at White Sox projected starters

TBD vs. RHP Chris Flexen

The Twins had not yet announced a starter, but there is a chance that RHP Chris Paddack (5-3, 5.29) comes off the IL and makes his 16th start. He has a 1.43 WHIP, 2.1 BB/9 and 8.0 K/9 in 78 1/3 innings.

  • Last start: No-decision, 4 2/3 IP, 3 ER, 5 H, 3 BB, 3 K in 6-5 loss at Oakland A’s June 21
  • 2024 road stats: 1-2, 7.84 ERA (31 IP, 27 ER), 1.58 WHIP, 6.4 K/9 in 6 starts
  • Career vs. White Sox: 1-0, 0.00 ERA (7 IP), 6 H, 0 BB, 10 K in 1 start, a 7-0 home win April 22

Flexen (2-7, 5.08 ERA) makes his 17th start and 19th appearance. He has a 1.39 WHIP, 3.5 BB/9 and 6.7 K/9 in 85 innings.

  • Last start: No-decision, 6 IP, 3 ER (6 R), 6 H, 1 BB, 3 K in 7-6 road loss to Cleveland Guardians Tuesday
  • White Sox have lost his last 9 starts
  • 2024 vs. Twins: 0-0, 3.68 ERA (7 1/3 IP, 3 ER), 1.09 WHIP, 4.9 K/9 in 2 appearances (1 start)
  • Career vs. Twins: 1-2, 3.94 ERA (29 2/3 IP, 13 ER), 1.32 WHIP, 7.6 K/9 in 6 appearances (5 starts)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Twins at White Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:12 a.m. ET.

  • Moneyline (ML): Twins -190 (bet $190 to win $100) | White Sox +155 (bet $100 to win $155)
  • Run line (RL)/Against the spread (ATS): Twins -1.5 (-115) | White Sox +1.5 (-105)
  • Over/Under (O/U): 9.5 (O: -105 | U: -115)

Twins at White Sox picks and predictions

Prediction

Twins 7, White Sox 4

Moneyline

The Twins (-190) have not lost to the White Sox all season. They are 24-21 on the road and 31-14 against teams that are .500 or worse.

The White Sox are 0-9 in Flexen’s last 9 starts and 2-14 in his starts all season.

The Twins should win, but betting them at -190 isn’t worth the action.

PASS.

Run line/Against the spread

Nine of the Twins’ last 10 wins have been by at least 2 runs. Four of their 7 wins over the White Sox have been by 2 or more runs.

Eleven of the White Sox’s 14 losses when Flexen starts have been by 2 or more runs.

BET TWINS -1.5 (-115).

Over/Under

The Twins have averaged 6.3 runs per game against the White Sox this season. Four of their last 5 games have had at least 10 total runs.

Five of  Chicago’s last 8 games have had totals of 10 or more.

BET OVER 9.5 (-105).

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