The Minnesota Twins (6-9) and Baltimore Orioles (10-6) play the middle Game of a 3-Game series Tuesday. First pitch from Oriole Park at Camden Yards is slated for 6:35 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Twins vs. Orioles odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 1-0

Twins starter RHP Louie Varland was knocked around by the Birds, allowing 11 H, 6 R (4 ER) in 5 IP in Monday’s 7-4 loss. 3B Jose Miranda went 3-for-4 with a HR, 2 RBI, and a run scored. Minnesota has lost 7 of its last 10 Games, scoring an average of just 3.5 runs per Game.

Baltimore got back to .500 on its 6-game homestand (2-2) with the series-opening win. Five Orioles had multi-hit performances, led by 3B Jordan Westburg‘s 3 hits, 2 RBI and a run scored. RHP Craig Kimbrel picked up his 4th save of the season, striking out 2 in a scoreless 9th.

Twins at Orioles projected starters

RHP Chris Paddack vs. RHP Grayson Rodriguez

Paddack (0-0, 4.15 ERA) makes his 3rd start. He has a 1.85 WHIP, 4.2 BB/9 and 7.3 K/9 in 8 2/3 innings.

  • Last start: No-decision, 4 2/3 IP, 2 ER, 6 H, 2 BB, 5 K in a 3-2 home victory against the Los Angeles Dodgers Wednesday
  • Last start vs Orioles: Win, 5 1/3 IP, 1 ER, 4 H, 1 BB, 3 K in a 2-1 road victory on May 2, 2022

Rodriguez (2-0, 2.50 ERA) makes his 4th start. He has a 1.17 WHIP, 2.5 BB/9 and 10.5 K/9 in 18 innings.

  • Last start: No-decision, 5 2/3 IP, 2 ER, 6 H, 2 BB, 5 K in a 9-4 victory at Boston Red Sox Thursday
  • Has never faced the Twins as a starter

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Twins at Orioles odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 11:28 p.m. ET.

  • Moneyline (ML): Twins +140 (bet $100 to win $140) | Orioles -166 (bet $166 to win $100)
  • Run line (RL)/Against the spread (ATS): Twins +1.5 (-146) | Orioles -1.5 (+122)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

Twins at Orioles picks and predictions

Prediction

Orioles 5, Twins 2

Moneyline

PASS.

The Orioles (-166) will get the victory in Game 2 of their series with the Twins (+140), but I’m not going to bet more than 1½ units. I’ll keep my wager to the spread.

Run line/Against the spread

BET ORIOLES -1.5 (+122).

I love this matchup for Baltimore against the righty Paddack. The Orioles are batting more than 30 points better against right-handers (.255) than lefties (.222). They have won 5 straight Games against Minnesota, covering the run line in 4 of those.

The Twins face Rodriguez who has the stuff to be an ace on most any team in MLB. Minnesota has struggled against righties; they are 5-6 and batting .179 on the season.

Over/Under

PASS.

My gut is telling me to take the Under because I like Rodriguez to shut down the Twins on Tuesday. The reason I’m avoiding it is because the Orioles have been Over in their last 6 Games. I don’t see an edge to give an official recommendation.

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