Uruguay vs. Colombia prediction, odds, line, start time: Copa America 2024 semifinal picks by soccer expert

Uruguay attempt to take another step toward a record 16th tournament title when they meet Colombia at Bank of America Stadium in Charlotte, NC, on Wednesday in the Copa America 2024 semifinals. Uruguay took the lead for the most championships in the competition's history when they defeated Paraguay in the 2011 final for their 15th, but Argentina pulled even when they got past Brazil for the crown in 2021. These two nations met in the quarterfinals that year, when they played to a 0-0 draw before the Colombians advanced on penalties.

Kickoff is set for 8 p.m. ET. Uruguay are +170 favorites (risk $100 to win $170) in the latest Colombia vs. Uruguay odds via SportsLine consensus, while the Colombians are +220 underdogs. A 90-minute draw is priced at +170 and the over/under for total goals scored is 1.5. Before locking in any Uruguay vs. Colombia picks, you need to see what proven SportsLine soccer insider Jon "Buckets" Eimer has to say.

Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, he has covered the English Premier League, Serie A, the FA Cup and much more. In 2023, he was red-hot, going 248-234-12 for a profit of $2,593 for $100 bettors.

Now, Eimer has broken down Colombia vs. Uruguay from every angle and locked in his picks and 2024 Copa America predictions. You can head to SportsLine now to see Eimer's picks. Here are the betting lines and trends for Uruguay vs. Colombia:

• Colombia vs. Uruguay money line: Colombia +220, Uruguay +170, Draw +170
• Colombia vs. Uruguay over/under: 1.5 goals
• Colombia vs. Uruguay spread: Uruguay -0.5 (+170)
  
• Colombia vs. Uruguay to advance: Colombia +100, Uruguay -122
• COL: The Colombians have scored three or more goals in six of their last nine matches across all competitions
• URU: The Uruguayans have posted a clean sheet in four of their last five overall contests
• Colombia vs. Uruguay picks: See picks here

Why you should back Colombia 

The Colombians enter with a 27-game unbeaten streak across all competitions (21-6-0), with their last defeat being a 1-0 loss to Argentina on Feb. 1, 2022, during World Cup qualifying. It matches the longest such run in national team history that was set from 1992-94 when Colombia registered 13 wins and 14 draws over a 27-game stretch. They tied the mark last Saturday with a 5-0 triumph over Panama in the quarterfinals, their largest margin of victory in a Copa America contest.

Colombia are the highest-scoring team in the competition with 11 goals, with eight different players having converted. Defender Daniel Munoz, winger Luis Diaz and forward Jhon Cordoba each have netted a pair of goals, with the latter two both scoring versus Panama. Also converting in that victory was midfielder James Rodriguez, who has tallied three times in five career meetings with Uruguay and leads all players in this tournament with five assists. See which team to pick here.

Why you should back Uruguay

While Colombia have scored a tournament-high 11 goals thus far, the Uruguayans are tied for first in the Copa America with just one goal allowed. That came during second-half stoppage time in the group-stage opener against Panama, as the team has posted three clean sheets since. Uruguay also have been strong at the other end of the pitch, as they are tied for second with nine goals - including two apiece by defender Maximiliano Araujo and forward Darwin Nunez.

Araujo will not be able to add to his total due to a leg injury suffered in the team's quarterfinal win against Brazil that has ended his tournament. But the 25-year-old Nunez will be on the pitch and looking to avoid a third consecutive match without a goal after enjoying a seven-game streak across all competitions during which he tallied 10 times. Veteran striker Luis Suarez has appeared in only half of Uruguay's four Copa America contests but is the country's all-time leader with 68 goals and ranks second with 140 games played. See which team to pick here.

How to make Uruguay vs. Colombia picks

Eimer has broken down Uruguay vs. Colombia from every possible angle and is leaning Over on the goal total. He also has locked in three confident best bets, including two that offer plus-money payouts, and is offering a full breakdown of this semifinal match. He's sharing his Copa America 2024 picks and analysis only at SportsLine.

So who wins Colombia vs. Uruguay on Wednesday, and where does all the betting value lie? Visit SportsLine now to see which wagers in Uruguay vs. Colombia have all the value, all from the soccer expert who was red-hot in 2023, and find out.

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