The San Diego Padres (56-50) and Baltimore Orioles (61-42) play Game 2 of a 3-Game series Saturday. First pitch from Oriole Park at Camden Yards is set for 4:05 p.m. ET (FS1). Let’s analyze FanDuel Sportsbook’s lines around the Padres vs. Orioles odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 1-0

Padres LF Jurickson Profar went deep twice Friday, the 2nd of which broke a 9th-inning tie and lifted San Diego to a 6-4 win as a +174 underdog with the Over (9) cashing by a run. It was the Padres’ 6th consecutive victory. 2B Xander Bogaerts went 3 for 4, including an RBI double as The Padres improved to 30-22 on the road this season and 55-51 against the spread (ATS).

Baltimore SP Grayson Rodriguez gave the Orioles a chance, allowing just 2 runs on 7 hits and no walks over 5 innings. The O’s could not get much going offensively besides solo home runs from RF Anthony Santander and 3B Jordan Westburg. Baltimore has lost 4 of their last 5 and are 13-17 during intraleague play this season.

Padres at Orioles projected starters

RHP Michael King vs. RHP Dean Kremer

King (8-6, 3.28 ERA) makes his 21st start and 22nd appearance. He has a 1.19 WHIP, 3.3 BB/9 and 10.3 K/9 in 118 innings.

  • Last start: Win, 7 IP, 1 ER, 2 H, 1 BB, 6 K in 2-1 victory at the Guardians Sunday
  • 2024 road splits: 7-2, 2.60 ERA (69 1/3 IP, 20 ER), 1.11 WHIP, 8.3 K/9 in 12 games
  • Career vs. Orioles: 2-1, 2.63 ERA (27 1/3 IP, 8 ER), 0.91 WHIP, 9.2 K/9 in 13 games (1 start)
  • Only start vs Orioles: No-decision, 4 IP, 3 ER, 4 H, 2 BB, 3 K in 6-5 road victory Sept. 4, 2020, as member of New York Yankees

Kremer (4-6, 4.43 ERA) makes his 14th start. He has a 1.22 WHIP, 3.7 BB/9 and 8.6 K/9 in 69 innings.

  • Last start: Loss, 5 1/3 IP, 3 ER, 5 H, 3 BB, 2 K in 3-2 defeat at Texas Rangers Sunday
  • 2024 home splits: 1-3, 6.16 ERA (30 2/3 IP, 21 ER), 1.53 WHIP, 8.5 K/9 in 6 starts
  • Only start vs Padres: Loss, 6 IP, 3 ER, 5 H, 2 BB, 4 K in 5-2 road setback August 16, 2023

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Padres at Orioles odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:07 a.m. ET.

  • Moneyline (ML): Padres +102 (bet $100 to win $102) | Orioles -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+158) | Orioles +1.5 (-192)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

Padres at Orioles picks and predictions

Prediction

Padres 5, Orioles 2

Moneyline

BET PADRES (+102).

The Padres are red hot right now. They’ve won 6 straight coming into Saturday’s game and I’m going to ride that momentum. The pitching staff has allowed just 7 total runs and tossed 3 shutouts over the 6-game run. King may not be their ace, but he’s won 3 of his last 4 starts allowing just 1 run in each for a 1.48 ERA (24 1/3 IP, 4 ER).

The Orioles are the better team, but right now they are in a bit of a funk coming out of the All-star break. Kremer is 1-4 over his last 6 starts with a 5.65 ERA (28 2/3 IP, 18 ER). These pitching woes is one of the reasons the Orioles bolstered their rotation Friday with the addition of RHP Zach Eflin in a trade with Tampa Bay.

Run line/Against the spread

PASS.

Since we’re backing the Orioles’ moneyline, let’s stay away from the run line.

Over/Under

BET UNDER 9 (-115).

The Under is 7-3 in the Padres’ last 10 games thanks mostly to superb pitching the last 2 weeks. Expect that to continue Saturday with King on the mound. The Under has hit in his last 3 starts.

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