AFC South opponents clash when the Houston Texans (5-2) host the Indianapolis Colts (4-3) on Sunday, October 27, 2024 at NRG Stadium. Houston is favored by 5 points. This contest has an over/under of 46.

See Game prop insights below in this article, including first to score, halftime score, and prop bets for the top players.

Texans vs. Colts game odds

NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 1:47 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Spread: Texans +5 (-110 to cover)
  • Moneylines: Texans -250, Colts +200
  • Total: 46 points (Over: -110, Under: -110)
  • Pick ATS: Texans (-5)
  • Pick OU: Under (46)
  • Prediction:
    Texans 26 – Colts 19

First TD odds and insights

First TD odds: Texans -190, Colts +140

  • The Texans have scored the first TD three times in seven games.
  • In those three games, one of Houston’s scores came rushing the ball, and two via the pass.
  • In the first quarter, the Texans have scored five touchdowns, the third-most in the league.
  • This year the Colts have scored the opening TD in five of their seven games.
  • In those five games when Indianapolis scored the first touchdown, it rushed for two and passed for three.
  • Looking at just first quarters, the Colts have scored five touchdowns, the third-most of all teams this year.
Watch the NFL Live on Fubo!

C.J. Stroud player props

  • Passing yard prop: Over/under 240.5 yards
  • C.J. Stroud racks up 237.6 passing yards per game this season, which is lower than his prop bet total for this matchup of 240.5.
  • Stroud has gone over on his passing yards prop bets two times this season.
  • Stroud has thrown for a touchdown six times this year in seven games played, including multiple TD passes three times.

Joe Mixon player props

  • Rushing yard prop: Over/under 76.5 yards
  • Sunday’s rushing yards over/under for Joe Mixon is set at 76.5. That’s 23.8 fewer yards than his season average of 100.3.
  • Mixon has hit the over on his rushing yards totals in three games (75.0%) out of four opportunities.
  • Mixon has rushed for at least one touchdown three times this season, including one game with multiple rushing TDs.