The Arizona Cardinals (1-1) will do their best to defy oddsmakers when they take on the Detroit Lions (1-1) on Sunday, September 22, 2024 as 3-point underdogs. This Game has a point total of 51.5.

Get insights on potential Game props in this article, including team to score first, halftime score, and player prop bet insights.

Lions vs. Cardinals game odds

NFL odds courtesy of BetMGM Sportsbook. Odds updated Friday at 10:13 a.m. ET. For a full list of Sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Spread: Lions +3 (-105 to cover)
  • Moneylines: Lions -150, Cardinals +125
  • Total: 51.5 points (Over: -110, Under: -110)
  • Pick ATS: Cardinals (+3)
  • Pick OU: Under (51.5)
  • Prediction:
    Cardinals 27 – Lions 22

First TD odds and insights

First TD odds: Lions -135, Cardinals +100

  • The Lions have scored the first TD one time this year out of two games played.
  • Each of Detroit’s one first touchdown was a rushing score.
  • In the first quarter, the Lions have not scored a touchdown this season.
  • This year the Cardinals have scored the opening touchdown two times (in two games).
  • Each of the two first touchdowns scored by Arizona was via a pass.
  • Looking at only first quarters, the Cardinals have scored three touchdowns, the second-most of all teams this year.
Watch the NFL Live on Fubo!

Jameson Williams player props

  • Receiving yard prop: Over/under 54.5 yards
  • Jameson Williams’ 100.0 receiving yards per game are 45.5 more than his prop bet over/under for Sunday’s game (54.5).
  • Williams has gone over on prop bets for receiving yards in both of his opportunities this season.
  • Williams has had a receiving touchdown in one of two games this season, but has no games with multiple receiving TDs.

David Montgomery player props

  • Rushing yard prop: Over/under 56.5 yards
  • Receiving yard prop: Over/under 7.5 yards
  • David Montgomery’s rushing yards over/under is set at 56.5 yards, compared to his season average of 63.0 yards per game.
  • Montgomery hit his rushing yards over once in two games played this season.
  • Montgomery has a rushing touchdown in all two games this year, but no games with multiple rushing TDs.

Kyler Murray player props

  • Passing yard prop: Over/under 234.5 yards
  • Rushing yard prop: Over/under 33.5 yards
  • Kyler Murray throws for 214.0 passing yards per game this season, which is lower than his prop bet over/under for this matchup of 234.5.
  • Murray has gone over his passing yard total once in two games with a prop available.
  • Murray has a passing touchdown in all two games this season, with multiple passing TDs in one of them.

James Conner player props

  • Rushing yard prop: Over/under 60.5 yards
  • Receiving yard prop: Over/under 13.5 yards
  • James Conner racks up 86.0 rushing yards per game this season, which outpaces Sunday’s prop total of 60.5 yards.
  • Conner has exceeded the rushing yards prop bet total set for him once in two opportunities this season.
  • Conner has a rushing touchdown in all two games this year, but no games with multiple rushing TDs.