NFL picks, MLB best bets and U.S. Open tennis predictions for Wednesday

Good morning, Pickswise Nation, and welcome to another wonderful Wednesday of Sports. The NFL season is nearly here, but we’ll still have to wait one more day for action to kick off. Today’s schedule features a mammoth MLB slate and more compelling Tennis at the U.S. Open, so let’s get straight to making your next bet better!

About Last Night

Cash another MLB parlay
The Pickswise MLB handicapping team has been rolling with our parlays of late, and that trend continued on Tuesday as we cashed another parlay, this one at +483 odds. This brings us to a whopping 5 parlay winners over the last 11 days! Certainly a profitable stretch and then some for our team. MLB props expert Javan Shouey also continued his strong run of late, cashing both of his picks to improve to 7-2 over his last 9 plays.

Marathon night match in New York
The US Open continued on Tuesday, and it was largely a day of routs. Novak Djokovic dominated Taylor Fritz, Coco Gauff rolled into her first semifinal in New York and Ben Shelton picked up a convincing victory over #10 seed Frances Tiafoe to qualify for his first-ever major semifinal against Djokovic on Friday.

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Today’s Slate

Action-packed day of MLB
Wednesday’s MLB slate features a number of compelling matchups, including the Mariners and Reds fighting for playoff positioning respectively, a battle in the AL West between the Astros and Rangers, as well as the conclusion of a pivotal series in the AL Central between the Twins and Guardians at 1:10 pm ET. Read today’s MLB predictions.

More action at the U.S. Open
There is plenty more action in the Tennis world at the U.S. Open in Queens, New York. Our expert Ricky Dimon has targeted Wednesday night’s showdown between Alexander Zverev and Carlos Alcaraz on Arthur Ashe Stadium as one of his plays of the day, so make sure you check out his US Open Day 10 best bets.

Best Bet of the Day

MLB: Detroit Tigers vs New York Yankees: NRFI (+100)
7:05 pm ET

While there are glimmers of optimism for the Tigers’ organization going forward, this offense is one of the worst in the league (28th in OBP, 29th in OPS) and went down without a whimper against Gerrit Cole. We should get another quick opening half of the inning with Clarke Schmidt on the mound for New York, as he just tossed a scoreless first inning against this very same lineup just last week. Opposing Schmidt is Matt Manning, who fared extremely well against this same Yankees lineup just last week (6 scoreless innings) and now has another opportunity to continue his fine form of late. Check out today’s MLB YRFI/NRFI best bets.

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Must-read

With plenty of MLB action on Wednesday, be sure to check out our MLB YRFI/NRFI best bets as our expert Caleb Wilfinger looks to continue his 29-11 run. We’ve already got plenty of Week 1 coverage for this upcoming NFL slate, including Prop Holliday’s Lions vs Chiefs player prop best bets for Thursday Night Football. Be sure to also familiarize yourself with our Pickswise NFL handicapping team for the upcoming season, along with the first edition of our NFL Power Rankings before Week 1 kicks off.

Looking for some early college football plays for Week 2? You’ve come to the right place, as we’ve analyzed the NCAAF Week 2 opening lines and have made 2 bets already. You can also read our U.S. Open Day 10 picks for today’s mouthwatering tennis action.

Read all our great Sports analysis as it arrives throughout the day on the Analysis tab.

Stat of the Day

Jose Altuve homered in 4 consecutive at-bats between his first 3 plate appearances on Tuesday and going back to Houston’s 13-6 win in the series opener on Monday.

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