The New Orleans Saints (2-5) and LA Chargers (3-3) meet in Week 8 Sunday. Kickoff from Highmark Stadium is set for 4:05 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Saints vs. Chargers odds, and make our expert NFL picks and predictions.

The Saints dropped their 5th straight game in Week 7, losing 33-10 to the Denver Broncos at home. They missed the 2.5-point cover as the Over (37) hit. New Orleans’ defense, which has allowed 84 points over the last 2 games, allowed the Broncos to rush for 225 yards. QB Spencer Rattler lost 2 fumbles, including 1 returned for a TD, before being replaced by QB Jake Haener, who threw a late TD to WR Cedric Wilson.

The Chargers lost 17-15 to the Arizona Cardinals in Week 7, their 3rd loss in the last 4 Games. They failed to cover as a 1-point road favorite while the Under (44.5) easily cashed. Offensively, L.A. could only muster 5 field goals from K Cameron Dicker, including 2 from over 50 yards. Despite QB Justin Herbert throwing for a season-high 349 yards (27-of-39), the Chargers struggled to contain the Cardinals’ ground Game, allowing an average of 6.2 yards per carry and 181 yards total.

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Saints at Chargers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated at 1:08 a.m. ET.

  • Moneyline (ML): Saints +280 (bet $100 to win $280) | Chargers -350 (bet $350 to win $100)
  • Against the spread (ATS): Saints +7 (-105) | Chargers -7 (-115)
  • Over/Under (O/U): 41 (O: -110 | U: -110)

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Saints at Chargers key injuries

Saints

  • QB Derek Carr (oblique) doubtful
  • OG Nick Saldiveri (shoulder) out
  • WR Cedrick Wilson (hip) out

Chargers

  • LB Joey Bosa (hip) questionable
  • WR D.J. Chark (groin) questionable
  • WR Derius Davis (hamstring) doubtful
  • TE Will Dissly (shoulder) questionable
  • WR Hayden Hurst (groin) questionable
  • WR Quentin  Johnston (ankle) doubtful
  • WR Ladd McConkey (hip) questionable
  • LB Denzel Perryman (toe) questionable

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Saints at Chargers picks and predictions

Prediction

Chargers 24, Saints 14

Moneyline

PASS.

The Chargers (-350) will take care of business on Sunday against a beat-up Saints squad. I’m not interested in betting more than 3 units to win 1, I’ll take my bet to the spread.

Against the spread

BET CHARGERS -7 (-115).

The Saints are struggling as they approach the season’s midpoint. Carr’s status remains uncertain, as he has yet to practice without pain. The loss of WR Rashid Shaheed for the season is a major setback for the Saints’ offense, which struggled without his deep-threat ability, evident in their underwhelming performance against Denver, averaging less than six yards per pass play.

Meanwhile, the Chargers’ top-ranked defense should dominate against a Saints’ offense that lacks explosive playmaking. Defensively, New Orleans has faltered, now ranked last in total defense and 26th in scoring defense. The Chargers have shown they can move the ball, but have struggled to finish drives. Against a porous Saints defense, those issues should ease. Expect the Chargers to set the tempo, pressure the Saints QB, and build a lead, allowing them to control the game through their rushing attack.

Over/Under

BET UNDER 41 (-110).

The Chargers have hit the Under in 5 of their 6 games this season, largely due to their stifling defense, which allows just 13.8 points per game—the lowest in the NFL. Meanwhile, the Saints have struggled offensively, averaging 17.2 points over their last 5 games and scoring under 15 in 2 of their last 3. Opponents are keying in on stopping RB Alvin Kamara, forcing rookie backup QB Rattler to beat them through the air. With LA’s focus on running the ball and controlling the clock, expect another low-scoring game.

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