The Minnesota Twins (63-49) and Chicago Cubs (56-60) meet Wednesday in the finale of a 3-game series. First pitch from Wrigley Field is set for 2:20 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the Twins vs. Cubs odds and make our expert MLB picks and predictions for the best bets.
Season series: Tied 1-1
Chicago beat Minnesota 7-3 Tuesday as a -108 favorite. LHP Shota Imanaga allowed 2 earned runs on 2 hits and 1 walk with 10 K’s — tying a career high — in 7 innings. Cubs 3B Isaac Paredes went 2-for-4 with 4 RBIs, including a 3-run shot in the 1st inning.
Twins RHP Pablo Lopez gave up 4 earned runs on 7 hits and 1 walk with 2 K’s in 5 innings. Tuesday’s loss ended a 5-game Twins win streak.
Twins at Cubs projected starters
RHP Joe Ryan vs. RHP Javier Assad
Ryan (7-7, 3.59 ERA) makes his 23rd start. He has a 0.33 WHIP, 1.6 BB/9 and 9.8 K/9 through 133 innings.
- Last start: Win, 6 1/3 IP, 2 ER, 3 H, 3 BB, 7 K in 10-2 home victory over Chicago White Sox Friday
- 2024 road stats: 2-4, 3.26 ERA (66 1/3 IP, 24 ER), 1.03 WHIP, 10.0 K/9 in 11 starts
- Career vs. Cubs: 2-1, 2.81 ERA (16 IP, 5 ER), 0.81 WHIP, 14.6 K/9 in 3 starts, including 0-1 with 0.00 ERA (6 IP) in 1 start last year
Assad (5-3, 3.19 ERA) makes his 21st start. He has a 1.37 WHIP, 4.1 BB/9 and 8.1 K/9 through 98 2/3 innings.
- Last start: No-decision, 4 IP, 1 ER, 4 H, 3 BB, 3 K in 6-3 home win vs. St. Louis Cardinals Friday
- 2024 home stats: 2-1, 2.20 ERA (49 IP, 12 ER), 1.41 WHIP, 7.3 K/9 in 10 starts
- Never faced Twins before
Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.
Twins at Cubs odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 11:49 p.m. ET.
- Moneyline (ML): Twins -134 (bet $134 to win $100) | Cubs +114 (bet $100 to win $114)
- Run line (RL)/Against the spread (ATS): Twins -1.5 (+134) | Cubs +1.5 (-162)
- Over/Under (O/U): 7 (O: -106 | U: -114)
Twins at Cubs picks and predictions
Prediction
Twins 6, Cubs 5
Moneyline
LEAN TWINS (-134).
Minnesota is 6-4 in the last 10 meetings, including 3-1 in the last 4, and 4-1 in the last 5 at Wrigley Field.
This is a lean because Minnesota is only 3-4 in its last 7 road games on the season, while the Cubs are 4-2 in their last 6 at home.
Run line/Against the spread
PASS.
I like the Cubs to cover here as +1.5 (-162) home underdogs, but they’re being slightly overvalued in this spot. Bet the ML and/or O/U instead.
Over/Under
BET OVER 7 (-106).
The Over has hit in 2 of Minnesota’s last 3 road games and is 6-3-1 in its last 10 overall.
For Chicago, the Over is 4-2 in its last 6 home games and 6-4 in its last 10 overall.
The Over has also hit in 6 of the last 7 meetings, including 3 of the last 4 in Chicago.
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