The Los Angeles Angels and Baltimore Orioles face off on Opening Day Thursday. First pitch from Oriole Park at Camden Yards is slated for 3:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Angels vs. Orioles odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Orioles won 5-2 last season

There are very low expectations for the Angels in 2024. BetMGM Sportsbook has their Over/Under win total set at just 72.5 Games. They won 73 Games in 2023, and they lost their best player in the offseason to the Dodgers, DH/RHP Shohei Ohtani. Los Angeles is hoping to get a full Healthy season from CF Mike Trout, which hasn’t happened since 2016. It’s going to be a long season for the Halos in 2024.

There are huge expectations for this Orioles squad that surprised everyone winning over 100 games and taking the AL East crown for the 1st time since 2014. They won’t surprise anyone this season but bring back all of their young talented core like C Adley Rutschman, 1B Ryan Mountcastle, 3B Gunnar Henderson, and LF Austin Hays. Baltimore also traded for 2021 NL Cy Young winner RHP Corbin Burnes to anchor its rotation. It’s World Series or bust for the Orioles in 2024.

Angels at Orioles projected starters

LHP Patrick Sandoval vs. RHP Corbin Burnes

Sandoval (7-13, 4.11 ERA in 2023) makes his 1st start. He had a 1.51 WHIP, 4.6 BB/9 and 8 K/9 in 144 2/3 innings.

  • 2023 road stats: 5-7, 3.81 ERA (78 IP, 33 ER) in 16 starts
  • Last start vs. Orioles: Loss, 5 IP, 4 ER (7 R), 7 H, 4 BB, 3 K in 10-3 home loss Sept. 6, 2023
  • Career vs. Orioles: 0-2, 3.86 ERA (16 1/3 IP, 7 ER) in 3 starts

Burnes (10-8, 3.39 ERA in 2023) makes his 1st start. He had a 1.07 WHIP, 3.1 BB/9 and 9.3 K/9 in 193 2/3 innings with the Milwaukee Brewers.

  • 2023 home stats: 4-3, 4.28 ERA (80 IP, 38 ER), .223 OBA in 14 starts
  • Career vs. Angels: Win, 6 IP, 1 ER, 5 H, 1 BB, 5 K in 1 start, a 7-5 home victory with the Brewers April 29, 2023

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Angels at Orioles odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 11:10 p.m. ET.

  • Moneyline (ML): Angels +150 (bet $100 to win $150) | Orioles -185 (bet $185 to win $100)
  • Run line (RL)/Against the spread (ATS): Angels +1.5 (-135) | Orioles -1.5 (+110)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

Angels at Orioles picks and predictions

Prediction

Orioles 4, Angels 1

Moneyline

PASS.

The Orioles (-185) will win on Opening Day against the Angels, but I’m not going to put down almost 2 units to win 1; it’s just not a smart bet. Save your money for the spread and/or the total.

Run line/Against the spread

BET ORIOLES -1.5 (+110).

It would be a real stunner if Baltimore dropped its home opener in front of a raucous crowd at Camden Yards. It has its newly-acquired ace taking the mound against what should be 1 of the worst lineups in the American League. I love this bet, and you should too.

Over/Under

BET UNDER 7.5 (-105).

These teams are wound tight on Opening Day, and it usually takes a bit for them to get warmed up. You’ve also got a top-tier pitcher on the mound for the Orioles against a sub-par lineup. Baltimore hit .259 against left-handed pitchers in 2023, and Sandoval is winless against the Orioles in his career.

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