Colombia vs. Uruguay prediction, odds, line, start time: Copa America 2024 semifinal picks by soccer expert

Colombia hope to set a record and advance to the final for the first time in more than two decades when they face Uruguay at Bank of America Stadium in Charlotte on Wednesday in the 2024 Copa America semifinals. Colombia, whose most recent final appearance in the tournament came when they won their lone title in 2001, routed Panama 5-0 in the quarterfinals to extend their unbeaten streak across all competitions to 27 contests (21-6-0) - matching the team mark set from 1992-94. Uruguay are even with Argentina at 15 Copa America championships and kept alive their chance to take the all-time lead by defeating Brazil on penalties in the quarters. These sides met in the 2021 quarterfinals, with the Colombians advancing on penalties.

Kickoff is set for 8 p.m. ET. Uruguay are +185 favorites (risk $100 to win $185) in the latest Colombia vs. Uruguay odds via SportsLine consensus, while the Colombians are +195 underdogs. A 90-minute draw is priced at +175 and the over/under for total goals scored is 1.5. Before locking in any Uruguay vs. Colombia picks, you need to see what proven SportsLine soccer insider Jon "Buckets" Eimer has to say.

Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, he has covered the English Premier League, Serie A, the FA Cup and much more. In 2023, he was red-hot, going 248-234-12 for a profit of $2,593 for $100 bettors.

Now, Eimer has broken down Colombia vs. Uruguay from every angle and locked in his picks and 2024 Copa America predictions. You can head to SportsLine now to see Eimer's picks. Here are the betting lines and trends for Uruguay vs. Colombia:

• Colombia vs. Uruguay money line: Colombia +195, Uruguay +185, Draw +175
• Colombia vs. Uruguay over/under: 1.5 goals
• Colombia vs. Uruguay spread: Uruguay -0.5 (+180)
  
• Colombia vs. Uruguay to advance: Colombia -110, Uruguay -110
• COL: The Colombians have scored three or more goals in six of their last nine matches across all competitions
• URU: The Uruguayans have posted a clean sheet in four of their last five overall contests
• Colombia vs. Uruguay picks: See picks here

Why you should back Colombia 

The Colombians have not tasted defeat since Feb. 1, 2022, when they dropped a 1-0 decision to Argentina during 2022 World Cup Qualifying. The team has won 11 of its last 12 matches across all competitions, outscoring opponents 29-7 in those victories. Colombia rank first in Copa America with 11 goals and have conceded only twice over their four contests.

Forward Jhon Cordoba, defender Daniel Munoz and winger Luis Diaz have netted two goals apiece in the tournament. Cordoba and Diaz were among the scorers in the quarterfinal triumph over Panama, as was captain James Rodriguez. The 32-year-old midfielder, who has converted three times in five career meetings with Uruguay, has notched a tournament-leading five assists - making him just the second player to reach that amount since the statistic became available in 2011. See which team to pick here.

Why you should back Uruguay

The Uruguayans have reached the semifinals for the first time since winning their last Copa America title in 2011. The side is tied for second in the competition with nine goals, all of which it recorded during the group stage. Uruguay's defense also has been stellar, as the club shares the lead with just one goal allowed.

Forward Darwin Nunez and defender Maximiliano Araujo lead Uruguay with two goals apiece, but the latter will miss the remainder of the tournament with a leg injury he suffered against Brazil in the quarterfinals. The 25-year-old Nunez has netted 13 goals in 27 career matches with the national team, including five in as many games this year. Five other players have converted for Uruguay in this competition - including defender Mathias Olivera, who scored his second career international goal in the 1-0 group-stage victory against the United States. See which team to pick here.

How to make Uruguay vs. Colombia picks

Eimer has broken down Uruguay vs. Colombia from every possible angle and is leaning Over on the goal total. He also has locked in three confident best bets, including two that offer plus-money payouts, and is offering a full breakdown of this semifinal match. He's sharing his Copa America 2024 picks and analysis only at SportsLine.

So who wins Colombia vs. Uruguay on Wednesday, and where does all the betting value lie? Visit SportsLine now to see which wagers in Uruguay vs. Colombia have all the value, all from the soccer expert who was red-hot in 2023, and find out.

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