College Football Week 4 opening lines, odds and best bet | Pickswise

College football Week 3 was one of the weaker slates of the season thus far, but we still had plenty of upsets and come-from-behind thrillers across the CFB landscape. A few statements were made too. Texas kept rolling without Quinn Ewers, Oregon rolled against Oregon State and Indiana thrashed UCLA in its Big Ten opener.

With Week 3 in the rearview mirror, it’s time to turn our attention to Week 4. Outside of the top Games, this slate isn’t as deep as some of the weeks to follow, but there is still plenty of compelling action for NCAAF fans to enjoy. These lines opened on Sunday and have already seen plenty of movement, so let’s take a look at the college Football Week 4 odds and lines, and give our first impressions. You can also find our college Football picks for all of the week’s biggest matchups.

NCAAF Week 4 opening lines and odds

Odds courtesy of DraftKings Sportsbook and available at time of publishing. 

• South Alabama +7.5 (-110) vs Appalachian State – Thursday, September 19
• Illinois +8.5 (-110) vs Nebraska – Friday, September 20
• San Jose State +14.5 (-110) vs Washington State – Friday, September 20
• FAU +12.5 (-110) vs Michigan State – Saturday, September 21
• Tennessee -7.5 (-110) vs Oklahoma – Saturday, September 21
• NC State +17 (-110) vs Clemson – Saturday, September 21
• Utah +3 (-115) vs Oklahoma State – Saturday, September 21
• UCLA +22.5 (-110) vs LSU – Saturday, September 21
• Iowa -2.5 (-110) vs Minnesota – Saturday, September 21
• Kansas +2.5 (-110) vs West Virginia – Saturday, September 21
• Florida -4.5 (-110) vs Mississippi State – Saturday, September 21
• USC -5.5 (-110) vs Michigan – Saturday, September 21
• Rutgers +4.5 (-110) vs Virginia Tech – Saturday, September 21
• Georgia Tech +10.5 (-110) vs Louisville – Saturday, September 21
• Arkansas +4 (-110) vs Auburn – Saturday, September 21
• TCU -2.5 (-110) vs SMU – Saturday, September 21x
• Miami FL -17.5 (-110) vs South Florida – Saturday, September 21
• California +2.5 (-110) vs Florida State – Saturday, September 21
• Baylor +1.5 (-110) vs Colorado – Saturday, September 21
• Purdue +6 (-110) vs Oregon State – Saturday, September 21
• Kansas State -7.5 (-110) vs BYU – Saturday, September 21

We’ll have NCAAF predictions for all the big games this week!

Best early bet for college football Week 4

San Jose State +14.5 over Washington State Cougars (-110)

Odds available at FanDuel Sportsbook at time of publishing.

One of my favorite situational spots of the week comes on Friday night when Washington State will host San Jose State. The Cougars are fresh off a terrific win as underdogs in the Apple Cup against in-state rival Washington in a Game that came down to the final seconds. Now, Washington State will return home for an interestingly placed Game against a mid-tier Mountain West opponent with a road Game against Boise State on deck. That’s a pretty difficult sandwich spot to handle for any team, and San Jose State could give the Cougars a real scare in this one.

The Spartans have quietly exceeded expectations to this point, sitting with a 3-0 record straight up and against the number. San Jose State has found an offense, as quarterback Emmett Brown has 9 touchdowns and nearly 1,000 passing yards through 3 games. However, the real star is wideout Nick Nash, who already has 6 touchdowns this season and is coming off a 17-catch effort in Week 3. The Spartans should hang tough on both sides of the ball, especially if Washington State comes out a bit sluggish. Don’t be surprised if this one gets very interesting in the second half.