Christina Applegate candidly shares she wears diapers while battling ‘s–tty’ MS

Christina Applegate candidly shared that she wears diapers while battling multiple sclerosis.

The “Dead to Me” star and her close pal Jamie-Lynn Sigler, who also has MS, were asked about the challenges that come with having the autoimmune disease during a joint interview with People published Wednesday.

“Well, you pee … in your pants,” Applegate responded. “Because you probably can’t get to the bathroom in time. So yeah, diapers.”

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The magazine reported that the “Married… with Children” alum — who was diagnosed with MS in 2021 but said on “Good Morning America” this week that she “probably had it for six or seven years” prior — yanked down the waistband of her jeans to reveal she was wearing a diaper adorned with a floral design during the interview.

Sigler, who revealed in 2016 that she was diagnosed with MS when she was 20, chimed in that she is not a fan of the options for diaper designs.

“We have a bone to pick with the designers, because who wants a beautiful flower on your diaper? It should really say ‘F–k my life,'” she joked.

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Applegate, 52, and the “Sopranos” alum, 42, clearly like to stay positive about their condition, as they hilariously pointed out some of the “benefits” of having MS.

“First of all, parking is awesome,” the “Samantha Who?” star said, to which Sigler agreed, “There could be a cure for MS, and I will not give up my handicap placard. We earned it!”

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Applegate also shared that having “wheelchair seating,” getting to board airplanes early and being pushed around airports is “awesome.”

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“But I put my hat down. I’m embarrassed,” the “Big Sky” star added of being pushed in a wheelchair at an airport.

Applegate agreed, “I wear a mask. I don’t let people see.”

In recent years, the actresses have turned to each other while coping with the hardships of the disease and formed a moving bond over their shared struggles.

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“We’re in two very different places with MS, but we help each other. Christina opened me up,” Sigler shared. “I didn’t realize how desperately I needed to stop trying to be perfect. One thing I haven’t done in the last 23 years is admit it was hard, because I didn’t want to let anyone down.”

Applegate, who called her battle “s–tty,” noted that she can be completely honest with Sigler because they know the same pain.

“She’s the only person who really knows me,” she said. “I can talk about anything with her. Constipation, diarrhea … Bravo TV.”