The Chicago White Sox (3-18) take on the Minnesota Twins (7-13) Monday in the opener of a 4-Game set at Target Field at 7:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the White Sox vs. Twins odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Twins won 9-4 last year

The White Sox are becoming an abomination, losers of 9 of 10, and they kept it within a run in just 1 of those losses. 3B Yoan Moncada (thigh) and OF Luis Robert Jr. (hip) are on the IL, and the White Sox are last with 2.1 runs/game, a .188 BA, .264 OBP and .288 SLG%.

The Twins are also flailing with SS Carlos Correa (oblique) out. They’ve lost 6 of 7, and the Twins are 28th with 3.4 R/game and 29th with a .195 BA. OF Byron Buxton is hitting just .217 with no homers and 9 RBIs on the young season. On the plus side, though, the Twins have beaten the White Sox in 7 of 8 games.

White Sox at Twins projected starters

RHP Jonathan Cannon vs. RHP Chris Paddack

Cannon allowed 1 ER on 3 H, 1 BB and struck out 3 in 5 IP in a no-decision against the Kansas City Royals Wednesday in his major-league debut.

  • 2024 stats with Charlotte (AAA): 0-0, 2.79 ERA, 1.55 WHIP and 11 K in 9 2/3 IP in 2 GS
  • Utilizes a 4-seam fastball (95 mph), a sinker, sweeper, cutter and changeup

Paddack (0-1, 8.36 ERA) makes his 4th start. He has a 2.07 WHIP, 3.2 BB/9 and 5.8 K/9 in 14 IP.

  • Last start: Loss, 5 1/3 IP, 9 ER, 12 H, 1 BB, 2 K Tuesday against Baltimore Orioles
  • Has never faced White Sox

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White Sox at Twins odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:10 p.m. ET.

  • Moneyline (ML): White Sox +165 (bet $100 to win $165) | Twins -200 (bet $200 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-120) | Twins -1.5 (+100)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

White Sox at Twins picks and predictions

Prediction

Twins 4, White Sox 2

Moneyline

The Twins are heavy favorites for good reason, but we’re not taking a 7-13 team at -200.

PASS and look to the spread.

Run line/Against the spread

We mentioned in the opener that of the White Sox’s 9 losses in the last 10 games, 8 of them were by multiple runs.

The Twins’ offense is nothing to write home about since it has scored more than 4 runs once in 10 Games. The White Sox have scored 11 runs in 6 Games.

Take the TWINS -1.5 (+100).

Over/Under

The White Sox are 5-5 O/U in their last 10, and the Twins are 5-4-1. With both teams struggling to score runs, this one goes UNDER 8.5 (-115).

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