The Carolina Panthers (1-6) and the Denver Broncos (4-3) meet for a Week 8 game at Empower Field at Mile High Sunday. Kickoff is scheduled for 4:25 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Panthers vs. Broncos odds, and make our expert NFL picks and predictions.

The Panthers were waffled 40-7 against the Washington Commanders last weekend, dropping a 4th straight game under QB Andy Dalton. The latter suffered a sprained thumb in a fender bender earlier this week, so the team will switch back to QB Bryce Young for Sunday’s game.

It’s a tough spot for Carolina and Young, no matter who is under center. The Denver Broncos pass defense ranks fifth in the NFL, and WR Diontae Johnson will be sidelined with a rib injury. That is going to make a tough matchup even worse for Young and the Panthers pass attack.

The Broncos have been rolling along under rookie QB Bo Nix, however, winning 4 of the past 5 games, while also going 4-1 against the spread (ATS). That including a 2-0 SU/ATS mark in 2 tries against NFC South teams so far this season, averaging 29.5 PPG in those games, while allowing just 8.5 PPG.

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Panthers at Broncos odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 9:46 p.m. ET.

  • Moneyline (ML): Panthers +450 (bet $100 to win $450) | Broncos -600 (bet $600 to win $100)
  • Against the spread: Panthers +11 (-110) | Broncos -11 (-110)
  • Over/Under (O/U): 41 (O: -110 | U: -110)

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Panthers at Broncos key injuries

Panthers

  • LB Jadeveon Clowney (shoulder) questionable
  • QB Andy Dalton (thumb) doubtful
  • S Sam Franklin Jr. (foot) out
  • S Jordan Fuller (hamstring) out
  • CB Dane Jackson (hamstring) doubtful
  • LB Josey Jewell (hamstring, groin) questionable
  • WR Diontae Johnson (rib) out
  • OL Taylor Moton (elbow) questionable
  • DE A’Shawn Robinson (knee) questionable
  • TE Tommy Tremble (back) questionable

Broncos

  • S P.J. Locke (thumb) doubtful
  • OT Alex Palczewski (ankle) questionable

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Panthers at Broncos picks and predictions

Prediction

Broncos 36, Panthers 9

Moneyline

The Broncos (-600) should roll in this game against the injury-depleted and toothless Panthers (+450) pass attack.

Carolina’s defense is terrible, but you can never risk 6 times your potential return, especially in an NFL game. That’s just not a recommended betting strategy over the long term.

PASS.

Against the spread

The BRONCOS -11 (-110) are a rare double-digit favorite this season. Denver is a strong play, however, as it has handled its business in 2 previous wins and covers against the NFC South Division.

Nix and the Broncos pass attack is rolling, and it should find very little resistance in the aerial Game, or on the ground, against the Panthers. The Carolina defense is historically bad, allowing 162.7 rushing yards and 34.7 PPG, both of which are last in the NFL.

Over/Under

OVER 41 (-110) is a strong look, and it’s possible Denver does most of the heavy lifting to get this across the finish line. It wouldn’t be surprising to see Denver keep Carolina to single digits, while still getting the total Over.

The Panthers defense has allowed 34 or more points in 4 straight games, and we’ve seen the Over cash in 4 of the previous 5 outings.

For the Broncos, they head into play with a 3-game Over run.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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