The Baltimore Orioles (76-56) and Los Angeles Dodgers (78-53) open a 3-game interleague set Tuesday. First pitch from Dodger Stadium is set for 10:10 p.m. ET (ESPN+). Let’s analyze FanDuel Sportsbook’s lines around the Orioles vs. Dodgers odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Dodgers won 2-1 in 2023

The Orioles split a 4-game set at home against the Houston Astros over the weekend. Baltimore has mostly been stuck in neutral in August, going 11-12 in the month. The Over and Under have alternated in the past 4 outings, with the Under going 8-4 across the past 12 contests.

For the O’s, they’re just 4-10 in the past 14 games against NL foes, too, with the Under going 3-1 in the past 4 interleague battles.

The Dodgers took 2 of 3 Games over the weekend from the visiting Tampa Bay Rays, and they’ve won 5 of the past 6 Games, all against AL teams. They’re 6-1 across the past 7 outings, with the Over going 3-1 in the past 4 affairs.

Orioles at Dodgers projected starters

LHP Cole Irvin vs. RHP Jack Flaherty

Irvin (6-5, 4.82 ERA) makes his 16th start and 23rd appearance. He has a 1.41 WHIP, 2.1 BB/9 and 6.2 K/9 in 99 IP.

  • Last start: No-decision, 4 1/3 IP, 2 ER, 5 H (1 HR), 2 BB, 2 K in 4-3 road loss vs. New York Mets last Wednesday
  • 2024 road splits: 3-1, 4.83 ERA (41 IP, 22 ER), 1.32 WHIP, .261 opponents’ batting average (OBA), 12 BB, 26 K in 9 appearances (6 starts)
  • Career vs. Dodgers: 0-0, 4.70 ERA (7 2/3 IP, 4 ER), 1.57 WHIP, 10.6 K/9 in 2 relief appearances

Flaherty (10-5, 3.00 ERA) makes his 23rd start. He has a 1.01 WHIP, 1.7 BB/9 and 11.3 K/9 in 129 IP with Tigers and Dodgers.

  • Last start: Loss, 4 1/3 IP, 3 ER, 4 H (1 HR), 4 BB, 5 K in 6-0 road setback vs. New York Yankees Thursday
  • 2024 home splits: 4-3, 3.60 ERA (55 IP, 22 ER), 1.15 WHIP, .246 OBA, 11 BB, 70 K in 9 starts with Detroit Tigers and Dodgers
  • 2024 with Dodgers: 3-0, 3.22 ERA (22 1/3 IP, 8 ER), 1.25 WHIP, .256 OBA, 5 BB, 29 K in 4 starts
  • Has never faced Orioles

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Orioles at Dodgers odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:04 p.m. ET.

  • Moneyline (ML): Orioles +160 (bet $100 to win $160) | Dodgers -190 (bet $190 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles +1.5 (-128) | Dodgers -1.5 (+106)
  • Over/Under (O/U): 8.5 (O: -120 | U: -102)

Orioles at Dodgers picks and predictions

Prediction

Dodgers 5, Orioles 2

Moneyline

The Dodgers (-190) are a little too expensive to bet straight up, especially in a battle between a pair of premier teams.

The Orioles (+160) are no pushover, and “Swervin” Cole Irvin is going to be pumped making his 1st start in his native Southern California. The Anaheim Servite High School pitcher has faced the Dodgers twice before, but both in relief, so expect him to start the Game with a little extra juice.

PASS.

Run line/Against the spread

The DODGERS -1.5 (+106) are a much better play on the run line, as they’ve played more consistent baseball than the Orioles +1.5 (-128) in the past month.

Flaherty has been a strikeout machine this season, and he is also a Southern California native having quite the resurgence with the Dodgers since being acquired from the lowly Tigers at the non-waiver trade deadline. His ERA and WHIP are actually up a touch since coming over from Detroit, but there is also much less pressure to be fine and perfect, as he gets much better offensive support.

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Over/Under

UNDER 8.5 (-102) is a good play, as these 2 SoCal pitchers should exchange plenty of donuts early before the bullpens take over.

The Dodgers’ bullpen rank 5th in the majors with a 3.57 ERA, while the O’s ‘pen checks in with a 4.10 ERA mark. That will be the difference with who wins the game, but the difference is rather slight. Once the starters are gone, don’t expect a watershed of runs.

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