TNF Week 6 NFL Picks, Predictions, Odds & Best Bets | Pickswise

NFL Week 6 has arrived and kicks off with a huge Thursday Night Football showdown between the San Francisco 49ers and Seattle Seahawks. Both teams suffered brutal losses last Sunday, as the 49ers blew a double-digit lead in the 4th quarter to fall to the Arizona Cardinals, while the Seahawks fell 29-20 to the New York Giants. As things stand, Seattle currently sits top of the division on 3-2 but San Francisco, which has surprisingly struggled through the first 5 weeks, can knock them off that spot if they get the win. Which team will stand tall in the NFC West at the end of the night?

49ers vs Seahawks kicks off at 8:15 pm ET live on Amazon Prime Video, and here at Pickswise, we have everything you need to bet better on this Thursday Night Football matchup, including NFL picks on the side and total, expert NFL player prop bets from props betting experts Prop Holliday and JutPicks, and even a 49ers vs Seahawks Same Game Parlay! Let’s get into our 49ers vs Seahawks picks and predictions for TNF.

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NFL TNF Picks

• San Francisco 49ers vs Seattle Seahawks predictions — find out our expert’s best bets on this side and total for TNF

49ers vs Seahawks best player prop bets

• 49ers vs Seahawks player prop picks — Prop Holliday has his best 49ers vs Seahawks prop bet locked in
• 49ers vs Seahawks touchdown scorer best bets — our expert is up +5.3 units on their TD scorer picks this season!

San Francisco 49ers vs Seattle Seahawks Same Game Parlay

• 49ers vs Seahawks Same Game Parlay –make it a Thursday to remember with our expert’s SGP picks at +728 odds, featuring Kenneth Walker and Jordan Mason!

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NFL Week 6 Predictions

Find out our expert best bets and predictions for EVERY NFL Week 6 matchup below:

• Jaguars vs Bears predictions
• Cardinals vs Packers predictions
• Browns vs Eagles predictions
• Texans vs Patriots predictions
• Buccaneers vs Saints predictions
• Commanders vs Ravens predictions
• Chargers vs Broncos predictions
• Falcons vs Panthers predictions
• Lions vs Cowboys predictions
• Bengals vs Giants predictions
• Bills vs Jets predictions