There were multiple upsets during Week 5 of the 2024 NFL season — continue reading for a complete list of which teams defied the odds.

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Biggest upsets of NFL week 5

NFL odds courtesy of BetMGM Sportsbook. Odds updated Tuesday at 8:16 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

The upsets ahead are sorted based on the pre-Game spread, with the larger upsets listed first.

Giants 29, Seahawks 20

  • Spread: Seahawks -7
  • Moneyline: Seahawks -350, Giants +260
  • Total: Over (42.5)

Cardinals 24, 49ers 23

  • Spread: 49ers -7
  • Moneyline: 49ers -350, Cardinals +280
  • Total: Under (49)

Cowboys 20, Steelers 17

  • Spread: Steelers -2.5
  • Moneyline: Steelers -145, Cowboys +120
  • Total: Under (44)