The Seattle Mariners (56-51) and the Boston Red Sox (55-49) open a 3-Game series Monday. First pitch from Fenway Park is at 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Mariners vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 2-2

The Mariners opened a 6-game road “Sox” series with a 3-game sweep of the Chicago White Sox over the weekend, outscoring the Pale Hose 22-6 and  cashing the Over in all 3 outings. Seattle has cashed the Over at a 9-3-2 pace in the past 14 road contests, too.

The Red Sox suffered 2 losses in 3 tries against the rival New York Yankees over the weekend, cashing the Over in all 3 contests. Boston was outscored 26-19 in the 3-game set, and Boston pitching has coughed up 7 or more runs in 7 of the past 8 outings. The Over is 7-1 since July 20.

These teams met for a season-opening 4-Game set in Seattle from March 28-31, with the teams splitting the series. The Over-Under also went 2-2, and 2 of the Games (both of the Seattle wins) were 1-run Games.

Mariners at Red Sox projected starters

RHP Logan Gilbert vs. RHP Nick Pivetta

Gilbert (6-6, 2.72 ERA) makes his 22nd start. He has a 0.86 WHIP, 1.7 BB/9 and 8.6 K/9 in 139 IP.

  • Last start: Loss, 6 IP, 5 R (1 ER), 4 H, 1 BB, 8 K in 5-1 home loss vs. Los Angeles Angels Tuesday
  • 2024 road splits: 4-2, 2.57 ERA (73 2/3 IP, 21 ER), 0.87 WHIP, .189 opponents’ batting average (OBA), 15 BB, 63 K in 11 starts
  • 2024 vs. Red Sox: No-decision, 7 IP, 1 ER, 4 H, 1 BB, 8 K in 4-3 win in 10 innings at T-Mobile Park March 30
  • Career vs. Red Sox: 0-0, 3.12 ERA (26 IP, 9 ER), 1.00 WHIP, 9.0 K/9 in 4 starts

Pivetta (4-7, 4.50 ERA) makes his 17th start. He has a 1.18 WHIP, 2.3 BB/9 and 10.9 K/9 in 84 IP.

  • Last start: Loss, 2 2/3 IP, 8 R (7 ER), 10 H (2 HR), 0 BB, 6 K in 20-7 road setback vs. Colorado Rockies Wednesday
  • 2024 home splits: 1-4, 5.50 ERA (36 IP, 22 ER), 1.33 WHIP, .241 OBA, 14 BB, 47 K in 7 starts
  • 2024 vs. Mariners: Loss, 6 IP, 1 ER, 3 H (1 solo HR), 0 BB, 10 K in 1-0 road setback March 29
  • Career vs. Mariners: 1-2, 3.65 ERA (24 2/3 IP, 10 ER), 0.89 WHIP, 10.9 K/9 in 4 starts

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Mariners at Red Sox odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:58 a.m. ET.

  • Moneyline (ML): Mariners -102 (bet $102 to win $100) | Red Sox -116 (bet $116 to win $100)
  • Run line (RL)/Against the spread (ATS): Mariners -1.5 (+152) | Red Sox +1.5 (-184)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

Mariners at Red Sox picks and predictions

Prediction

Mariners 6, Red Sox 4

Moneyline

The MARINERS (-102) are worth a look as short ‘dogs in this series opener, as Seattle sails in on a 3-game winning streak.

In addition, the M’s turn to Gilbert, who has been money on the road. He has a sparkling 2.57 ERA away from home, while Pivetta has been a disaster at Fenway Park this season.

Run line/Against the spread

If you’re a little more on the adventurous side, disregard the moneyline, and roll with SEATTLE -1.5 (+152) at plus-money. The M’s not only swept the White Sox over the weekend, but they managed to win by 3 or more runs and cashing against the run line in each of the outings.

On the flip side, Boston +1.5 (-184) has not only posted a dismal 2-7 mark in the past 9 games, it has lost 5 of those outings by 3 or more runs. In the past 9 games, the Red Sox have a terrible minus-22 run differential, too.

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Over/Under

BET OVER 8.5 (-110), which is a strong play based on the recent performances for both teams.

The Red Sox have cashed high in 4 straight, and 7 of the past 8 outings. Boston has coughed up 7 or more runs in 7 of the previous 8 contests, too.

For the M’s, the Over hit in the first 3 games of the road trip, and the total has gone high in 15-4-2 in the past 21 away from home.

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