At Wrigley Field on Wednesday, the Chicago Cubs (22-15) meet the San Diego Padres (19-20), with first pitch at 2:20 PM ET.

As the favorite, the Padres (-125 on the moneyline to win) take the field at the Cubs (+105). The Padres will start Dylan Cease (4-2) against the Cubs and Hayden Wesneski (2-0).

Yesterday, the Cubs claimed a 3-2 win over the Padres, with Hector Neris (1.0 IP, 0 R, 1 H, 0 K) registering the win for the Cubs. Cody Bellinger went 3-for-4 with a home run and an RBI to lead the offense. Enyel De Los Santos (0.1 IP, 1 R, 1 H, 0 K) was handed the loss for the Padres.

Get ready for the Padres vs. Cubs with everything you need to know about Wednesday’s Game, including viewing options.

San Diego Padres vs. Chicago Cubs odds and betting lines

MLB odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 9:16 AM ET. For a full list of Sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Favorite: Padres (-125, bet $125 to win $100)
  • Underdog: Cubs (+105, bet $100 to win $105)
  • Over/under: 8

Padres vs. Cubs: Live streaming info & game time

  • Game Day: Wednesday, May 8, 2024
  • Game Time: 2:20 PM ET
  • Stadium: Wrigley Field
  • TV Channel: Padres
  • Live Stream: Fubo (Watch for free)

Padres stats and trends

Padres betting records

  • This season, the Padres have been favored 23 times and won 12, or 52.2%, of those games.
  • San Diego has a record of 8-7 in games when bookmakers favor them by at least -125 on the moneyline.
  • Bookmakers have implied with the moneyline set for this matchup that the Padres have a 55.6% chance to win.
  • San Diego and its opponents have hit the over in 21 of its 39 games with a total this season.
  • In 38 games with a spread this season, the Padres are 20-18-0 ATS.

Dylan Cease (Padres probable starter)

  • The Padres will send Cease (4-2) to the mound to make his eighth start of the season. He is 4-2 with a 2.55 ERA and 48 strikeouts through 42 1/3 innings pitched.
  • His last time out came on Saturday against the Arizona Diamondbacks, when the righty went 6 2/3 innings, surrendering one earned run while giving up three hits.
  • In seven games this season, the 28-year-old has put up a 2.55 ERA and 10.2 strikeouts per nine innings, while allowing a batting average of only .140 to his opponents.
  • Cease is looking to pick up his sixth quality start of the season.
  • Cease will try to prolong a seven-game streak of going five or more innings (he’s averaging 6.0 frames per appearance).
  • He has held his opponents without an earned run in one of his seven outings this season.
  • He will take the hill against a Cubs squad that is hitting .238 as a unit (18th in MLB). It is also slugging a collective .395 (12th in MLB) with 40 total home runs (eighth in MLB).
  • Cease has thrown six innings without giving up an earned run on two hits, while striking out seven against the Cubs this season.
  • The 28-year-old ranks 16th in ERA (2.55), fifth in WHIP (.803), and 15th in K/9 (10.2) among qualifying pitchers in MLB play this season.

Padres batting stats

  • The Padres have hit 41 homers this season, which ranks seventh in the league.
  • Hitters for San Diego rank sixth in the majors with a combined .409 team slugging percentage.
  • The Padres’ .261 batting average is among the best in baseball, ranking second in MLB.
  • San Diego has scored 195 runs this season, which ranks second in MLB.
  • The Padres have an on-base percentage of .325 this season, which ranks sixth in the league.
  • San Diego ranks ninth in MLB in strikeouts per game with an average of 7.4 whiffs per contest.

Cubs stats and trends

Cubs betting records

  • The Cubs have won in 12, or 54.5%, of the 22 contests they have been named as odds-on underdogs this year.
  • Chicago has a mark of 9-7 in contests where oddsmakers favor it by +105 or worse on the moneyline.
  • The moneyline set for this matchup implies the Cubs have a 48.8% chance of coming away with a victory in the contest.
  • Chicago’s games have gone over the total in 16 of its 37 opportunities.
  • The Cubs have posted a record of 21-15-0 against the spread this season.

Hayden Wesneski (Cubs probable starter)

  • Wesneski (2-0) makes the start for the Cubs, his third of the season.
  • The righty last appeared on Friday against the Milwaukee Brewers, when he tossed 6 1/3 scoreless innings while giving up three hits.
  • In four games this season, he has a 0.54 ERA and 7.6 strikeouts per nine innings while opponents are batting .150 against him.
  • Wesneski is looking to secure his second quality start of the season.
  • Wesneski will try to secure his second matchup of five or more innings pitched this season. He averages 4.1 innings per appearance.
  • He has made three appearances this season in which he did not surrender an earned run.
  • He will face off against a Padres offense that ranks second in the league with 347 total hits (on a .261 batting average). The squad also slugs a collective .409 (sixth in the league) with 41 total home runs (seventh in MLB play).

Cubs batting stats

  • The Cubs rank eighth in baseball with 40 home runs. They average 1.1 per game.
  • So far this year, Chicago ranks 12th in the majors, slugging .395.
  • The Cubs have the 18th-ranked batting average in the majors (.238).
  • The offense for Chicago is No. 9 in baseball, scoring 4.7 runs per game (174 total runs).
  • The Cubs are 11th in MLB with an on-base percentage of .318.
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