The Philadelphia Phillies (45-20) and Boston Red Sox (33-33) open a 3-game series Tuesday. First pitch from Fenway Park is set for 7:10 p.m. ET (TBS). Let’s analyze FanDuel Sportsbook’s lines around the Phillies vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Boston won 2-1 last season

Philadelphia lost 6-5 to the New York Mets Sunday as a -142 home favorite. The Phillies allowed the Mets to score 3 runs in the 9th to blow a 4-3 lead.  Sunday’s loss ended a 4-game winning streak for Philly.

After back-to-back losses in Chicago, Boston picked up a 6-4 win in 10 innings over the White Sox Sunday while covering as a -147 road favorite. The Red Sox scored 3 runs in the 9th and 10th innings to come back from down 4-3.

Phillies at Red Sox projected starters

RHP Zack Wheeler vs. RHP Kutter Crawford

Wheeler (7-3, 2.23 ERA) makes his 14th start. He has a 0.97 WHIP, 2.9 BB/9 and 10.2 K/9 in 80 2/3 IP.

  • Last start: Win, 7 IP, 1 ER, 5 H, 3 BB, 6 K in a 3-1 win over Milwaukee on June 3
  • Career vs. Boston: 1-1, 3.55 ERA (12 2/3 IP, 5 ER), 10 H, 1 BB, 17 K in 2 starts

Crawford (2-5, 3.51 ERA) makes his 14th start. He has a 1.18 WHIP, 2.9 BB/9 and 8.6 K/9 in 74 1/3 IP.

  • Last start: Loss, 6 IP, 4 ER, 5 H, 2 BB, 5 K in an 8-3 loss vs. Atlanta Tuesday
  • First career start vs. Philadelphia

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Phillies at Red Sox odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 10:46 p.m. ET.

  • Moneyline (ML): Phillies -164 (bet $164 to win $100) | Red Sox +138 (bet $100 to win $138)
  • Run line (RL)/Against the spread (ATS): Phillies -1.5 (+105) | Red Sox +1.5 (-126)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

Phillies at Red Sox picks and predictions


Phillies 4, Red Sox 1



Avoid paying the juice and take the Phillies on the plus-money run line.

Run line/Against the spread

BET PHLLIES -1.5 (+105).

Philadelphia is 4-1 in its last 5 Games and is 7-3 in its last 10 while the Red Sox are only 5-5 in their last 10. Philly has also won the last 2 matchups vs. the Red Sox in Boston.

Also, 11 of the Phillies past 12 wins have been by multiple runs.


LEAN UNDER 8 (-105).

The Under has hit in 6 consecutive Games for Philadelphia and is 9-0-1 in its last 10 overall. For Boston, the Under hit in its last home Game and in its last loss. The Under is also 2-1-1 in the last 4 Philly-Boston matchups, hitting in the last meeting between these squads in Boston.

But be aware the Over is 7-3 in Boston’s last 10 Games.

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