Sportsbooks give the Jacksonville Jaguars (0-4) a small chance to halt their two-Game losing streak, as they are favored by 2.5 points in a matchup with the Indianapolis Colts (2-2) on Sunday, October 6, 2024 at EverBank Stadium. The contest’s point total is listed at 46.

See Game prop insights to parlay below in this article, including first to score, halftime score, and player prop bet insights.

Jaguars vs. Colts game odds

NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 1:45 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Spread: Jaguars +2.5 (-120 to cover)
  • Moneylines: Jaguars -150, Colts +125
  • Total: 46 points (Over: -110, Under: -110)
  • Pick ATS: Colts (+2.5)
  • Pick OU: Under (46)
  • Prediction:
    Colts 23 – Jaguars 20

First TD odds and insights

First TD odds: Jaguars -150, Colts +110

  • This year the Jaguars have scored the opening touchdown two times (in four games).
  • In those two games when Jacksonville notched the first TD, it passed for one and ran for one.
  • Looking at the first quarter only, the Jaguars have put two touchdowns on the board, 11th among all teams.
  • The Colts have scored the opening TD three times in four games.
  • In those three games, two of Indianapolis’ scores came rushing the ball, and one in the air.
  • Looking at only first quarters, the Colts have scored three touchdowns, the fifth-most of all teams this season.
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Trevor Lawrence player props

  • Passing yard prop: Over/under 234.5 yards
  • Sunday’s passing yards over/under for Trevor Lawrence is set at 234.5, 52.2 more yards than his season average of 182.3.
  • Lawrence has yet to hit the over on his passing yards prop bet this season in four chances.
  • Lawrence has a passing touchdown in three of four games this year, with multiple passing TDs in one of them.