Inter Miami welcomes Nashville SC to the Chase Stadium Wednesday evening in the 2nd leg of the CONCACAF Round of 16. Kickoff is set for 8:15 p.m. ET. Below, we preview FanDuel Sportsbook’s lines around the Inter Miami vs. Nashville SC odds, and make our best expert soccer picks and predictions.

With F Lionel Messi having rested against CF Montreal in Inter’s MLS match on Sunday, the home side appears all in for this match. Expect Messi to get a full 90 minutes. In the 1st leg, the result was a 2-2 draw in Nashville with Miami having exactly double the shots and shots on goal while owning 71% of the possession. Inter is 2-1-1 in MLS action.

Nashville is 0-3-0 (3 draws) in MLS action and is coming off a 2-2 draw with the LA Galaxy on the road. Through the 2 legs, it beat Moca a combined 7-0 in the 1st round of the Champions Cup. Nashville is again led this season by star F Hany Mukhtar, who netted 15 goals to along with 9 assists in MLS action last season.

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Inter Miami vs. Nashville SC odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:15 a.m. ET.

  • Moneyline:  Inter Miami -220 (bet $220 to win $100) | Nashville SC +490 (bet $100 to win $490) | Draw +330 (bet $100 to win $330)
  • Over/Under: 2.5 (O: -160 | U: +114)

Inter Miami vs. Nashville SC picks and predictions

Prediction

Inter Miami 3, Nashville SC 1

Moneyline (ML)

PASS.

Unfortunately, there’s no real value in betting on Inter Miami to win this game, but they played well at home and seem to have prepared to put their best product on the field.

They should come out on top, and backing goals to be scored may correlate with backing the home side, so look to the total for value instead of taking Inter at -220.

Over/Under (O/U)

BET OVER 3.5 (+148).

Inter Miami has an offense that is capable of scoring goals at a fast rate. Miami has scored at least 2 goals in 4 of its 5 matches throughout all competitions, and it has tallied 9 goals in its last 3 games (2 MLS and 1 CONCACAF Champions Cup). Inter has Messi and F Robert Taylor along with a strong and veteran midfield.

Similarly, Nashville already showed it can score on Miami and has the star power in Mukhtar to break through an aging Miami backline. Inter has allowed 5 goals in their last 2 Games while Nashville has netted 2 in each of its last 2.

Expect a high-scoring battle and take the  alternative OVER 3.5 (+148).

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