The Houston Astros (52-47) and Oakland A’s (39-62) begin a 3-game series Monday. First pitch from Oakland-Alameda County Coliseum is scheduled for 9:40 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Astros vs. A’s odds and make our expert MLB picks and predictions for the best bets.

Season series: Astros lead 6-1

The Astros were unable to cap off a 3-game sweep in Seattle, falling 6-4 against the Mariners Sunday after winning the 1st 2 games by a combined score of 7-2. Houston has picked up 6 wins in the past 9 games while going a respectable 8-4 across the past 12 outings on the road.

The A’s were cooled off 8-5 against the Los Angeles Angels Sunday as Oakland couldn’t complete the 3-Game series sweep. Still, the A’s ran their streak of 5 or more runs to 6 Games, averaging 9.2 runs per Game (RPG) during the span.

Houston has won 7 of the past 8 meetings since Sept. 13, 2023, with the A’s picking up a 3-1 win at home May 25 for the only victory in the span. The Under is 7-2-1 in the previous 10 meetings between these AL West rivals.

Astros at A’s projected starters

RHP Spencer Arrighetti vs. LHP Hogan Harris

Arrighetti (4-7, 5.63 ERA) makes his 18th start. He has a 1.60 WHIP, 5.0 BB/9 and 10.5 K/9 in 80 IP.

  • Last start: No-decision, 6 IP, 1 ER, 2 H (1 solo HR), 3 BB, 7 K in 2-1 home loss in 10 innings vs. Texas Rangers July 13
  • 2024 road splits: 1-5, 6.70 ERA (41 2/3 IP, 31 ER), 1.87 WHIP, .300 opponents’ batting average (OBA), 27 BB, 48 K in 9 starts
  • Career vs. A’s: 1-1, 4.50 ERA (10 IP, 5 ER), 10.8 K/9 in 2 starts this season

Harris (1-3, 3.40 ERA) makes his 9th start and 11th appearance. He has a 1.45 WHIP, 4.3 BB/9 and 6.6 K/9 in 47 2/3 IP.

  • Last start: No-decision, 3 IP, 2 ER, 3 H, 6 BB, 0 K in 6-2 road win vs. Philadelphia Phillies July 12
  • 2024 home splits: 1-2, 3.29 ERA (27 1/3 IP, 10 ER), 1.28 WHIP, .243 OBA, 10 BB, 17 K in 4 starts and 1 relief appearance
  • 2024 vs. Astros: No-decision, 3 1/3 IP, 0 R, 0 H, 2 BB, 3 K in 1 relief appearance of 8-1 road loss May 16
  • Career vs. Astros: 0-1, 1.26 ERA (14 1/3 IP, 2 ER), 0.56 WHIP, 8.8 K/9 in 1 start and 2 relief appearances

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Astros at A’s odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:48 a.m. ET.

  • Moneyline (ML): Astros -152 (bet $152 to win $100) | A’s +128 (bet $100 to win $128)
  • Run line (RL)/Against the spread (ATS): Astros -1.5 (+120) | A’s +1.5 (-144)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

Astros at A’s picks and predictions

Prediction

A’s 6, Astros 3

Moneyline

The A’S (+128) are a good bet if you’re a little more on the adventurous side.

The Astros (-152) have been playing better baseball lately after a dreadful start to the season, especially by their standards. However, Houston can’t be trusted with the erratic Arrighetti on the bump against an Oakland offense which has been surprisingly red-hot lately.

Run line/Against the spread

The A’S +1.5 (-144) are not priced out of line if you’re a little more conservative and would like some insurance. It’s hard to trust Oakland straight up, but Harris has been serviceable, and he handled the Astros in his previous relief appearance earlier this season.

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Over/Under

OVER 8 (-105) is the lean, but go with a half-unit play at most.

The reason to go high is Oakland’s offense lately, as it is averaging 9.2 RPG across the past 6 outings. And, it’s a good idea to play the Over against Arrighetti, who has been erratic, especially away from home.

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