The Denver Nuggets (2-2) and Minnesota Timberwolves (2-2) meet Friday at Target Center with tip-off set for 9:30 p.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s NBA odds around the Nuggets vs. Timberwolves odds and make our expert NBA picks and predictions for the best bets.

Season series: First meeting; Tied 2-2 last season

The Nuggets celebrated their second straight overtime win by edging the Brooklyn Nets 144-139 on Tuesday, but failed to cover as 5.5-point road favorites while the Over (218.5) hit. C Nikola Jokic, the reigning NBA MVP, showcased his skills with a triple-double, amassing 29 points, 18 rebounds, and 16 assists. F Aaron Gordon and G Jamal Murray each added 24 points.

The Timberwolves suffered their first loss at home on Tuesday, falling 120-114 to the Dallas Mavericks as 4-point favorites while the Over (220.5) cashed. G Anthony Edwards led with 37 points and 6 rebounds, while F Julius Randle added 20 points, 7 rebounds, and 7 assists. However, 20 turnovers proved costly for the Timberwolves.

Nuggets at Timberwolves odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NBA odds. Lines last updated at 12:39 a.m. ET.

  • Moneyline (ML): Nuggets +150 (bet $100 to win $150) | Timberwolves -190 (bet $190 to win $100)
  • Against the spread (ATS): Nuggets +4.5 (-115) | Timberwolves -4.5 (-105)
  • Over/Under (O/U): 220.5 (O: -110 | U: -110)

Nuggets at Timberwolves key injuries

Nuggets

  • F Vlatko Cancar (ankle) probable
  • F Aaron Gordon (knee) probable

Timberwolves

  • None

For most recent updates: Official NBA injury report.

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Nuggets at Timberwolves picks and predictions

Prediction

Timberwolves 122, Nuggets 115

Moneyline

PASS.

I’m backing Minnesota (-190) to handle the Nuggets (+150) at home, with their balanced offense and defense. Betting on the spread offers better odds for this matchup.

Against the spread

BET MINNESOTA -4.5 (-105).

The Timberwolves are 6-4 at home in the last 10 matchups against the Nuggets. With Denver’s early-season defensive struggles, Minnesota has a great chance to capitalize. The Timberwolves are locking down the perimeter, ranking third in limiting 3-point attempts and second in restricting makes, while also ranking ninth in defensive rebounds. Denver’s defense ranks 22nd, allowing 118.8 points per Game.

Over/Under

BET OVER 220.5 (-110)

Both teams are pushing a fast pace, averaging 104.7 possessions per game, which has frequently led to high scores. Denver has hit the Over in both of their road games this season, while Minnesota went Over in 2 of their last 3 games. With a combined O/U trend of 7-3 in Denver’s last 10 games in Minnesota, a projected total around 237 feels likely.

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