Cleveland Guardians vs Cincinnati Reds Prediction 9-25-24 MLB Picks

The Cincinnati Reds and the Cleveland Guardians meet Wednesday in MLB action from Progressive Field. Here’s a Cleveland Guardians vs Cincinnati Reds prediction. This will be the second installment in a two-Game series. We will look at this from a betting perspective and determine the best Guardians vs Reds pick.

Cincinnati Reds Betting Preview

Over the weekend the Reds took on the Pittsburgh Pirates. Cincinnati won the first pair in that set before a 2-0 loss Sunday. In the Tuesday opener versus Cleveland, the Reds were down 3-0 after one inning and never recovered in a 6-1 loss. Carson Spiers gave up three earned in 4.0 innings as a starter.

The starter for Wednesday will be Julian Aguiar. This year Aguiar is 2-1 with a 6.25 ERA over the first seven starts of his career.

Cleveland Guardians Betting Preview

Over on the Cleveland side, they played the St. Louis Cardinals in their last series. The Guardians won 5-1 in the opener of that set but lost the weekend Games. In the Tuesday matchup, Cleveland posted 10 team hits during the victory. Tanner Bibee was solid on 7.0 innings and one earned in the start.

Joey Cantillo will start for Cleveland on Wednesday. This year Cantillo is 2-3 with a 4.63 ERA in the first eight Games (seven starts) of his MLB career.

Total Runs Facts

• Seven of the last eight games between the Reds and Guardians have gone UNDER the total run line.
• Six of the Reds’ last seven road games against American League opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Guardians’ last three home games.

Cleveland Guardians Player Prop Facts

• Lane Thomas has hit a home run in each of the Guardians’ last two night games against opponents that held a losing record.
• Lane Thomas has recorded at least one RBI in five of the Guardians’ last six night games against opponents that held a losing record.
• Steven Kwan has scored at least one run in 10 of his last 12 appearances in night games against NL Central teams that held a losing record.
• Jose Ramirez has recorded at least one hit in each of the Guardians’ last 11 night games.
• Jose Ramirez has recorded at least one total base in each of the Guardians’ last 11 night games.
• Josh Naylor has recorded a Double in each of the Guardians’ last four night games against NL Central opponents that held a losing record.
• Josh Naylor has recorded at least one Single in each of his last six appearances against the Reds.

Cincinnati Reds Player Prop Facts

• Santiago Espinal has recorded a Double in each of his three previous road appearances against the Guardians after playing the previous day.
• TJ Friedl has recorded at least one Single in each of the Reds’ last six road games against opponents that held a winning record.
• Jake Fraley has hit a home run in three of his last four appearances against the Guardians after playing the previous day.
• Jeimer Candelario has recorded at least one RBI in each of his last four appearances against the Guardians.
• TJ Friedl has recorded at least one total base in each of his last 11 road appearances against AL Central opponents.
• Jeimer Candelario has scored at least one run in each of his last nine road appearances against AL Central opponents.
• TJ Friedl has recorded at least one hit in each of his last 11 road appearances against AL Central opponents.

Cleveland Guardians vs Cincinnati Reds

I’ll stay with the Guardians. Cantillo is on a nice run over his last three outings. In that trio, he’s 2-0 with just two earned runs in 16.1 total frames. As for Aguiar, he’s 1-1 in his last pair with 10 earned in 10.1 innings of work.

On Tuesday the Guardians got off to a hot start and rode the wave to a nice win. Cleveland got a couple of homers from Lane Thomas (three RBI) and Kyle Manzardo as well. I like another good all-around effort on Wednesday.