The Cleveland Guardians (49-26) and Baltimore Orioles (49-28) begin a 3-game series Monday. First pitch from Oriole Park at Camden Yards is scheduled for 6:35 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Guardians vs. Orioles odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Guardians won 4-3 last year

The Guardians completed a 3-game sweep of the Toronto Blue Jays Sunday, winning 6-5. Cleveland has won 5 straight outings, outscoring opponents 33-12 in the span. The Over is on a 4-1-1 run in the previous 6 outings.

With Cleveland’s win Sunday, it has a winning percentage of .653, slightly ahead of the New York Yankees (.650) for the best mark in the American League.

The Orioles were swept in 3 Games on the road against the Houston Astros, getting outscored 27-13, and that was with 11 runs scored in Friday’s series opener loss. The Over is 6-2-2 in the past 10 Games for Baltimore.

Guardians at Orioles projected starters

RHP Tanner Bibee vs. LHP Cade Povich

Bibee (5-2, 3.65 ERA) makes his 16th start. He has a 1.13 WHIP, 2.3 BB/9 and 10.9 K/9 in 81 1/3 IP.

  • Last start: Win, 6 IP, 0 ER, 3 H, 1 BB, 12 K in 8-0 home victory vs. Seattle Mariners Wednesday
  • 2024 road splits: 2-1, 2.84 ERA (38 IP, 12 ER), 1.11 WHIP, .218 opponents’ batting average, 5 HR, 11 BB, 46 K in 7 starts

Povich (0-1, 3.94 ERA) makes his 4th start. He has a 1.25 WHIP, 5.1 BB/9 and 5.1 K/9 in 16 IP.

  • Last start: No-decision, 4 2/3 IP, 1 ER, 1 H, 5 BB, 1 K in 7-6 road win in 10 innings vs. Yankees Wednesday
  • Career home splits (1 start): No-decision, 6 IP, 0 ER, 5 H, 0 BB, 6 K in 4-2 home win vs. Atlanta Braves June 12

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Guardians at Orioles odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 11:55 p.m. ET.

  • Moneyline (ML): Guardians -105 (bet $105 to win $100) | Orioles -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Guardians -1.5 (+155) | Orioles +1.5 (-190)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

Guardians at Orioles picks and predictions

Prediction

Guardians 5, Orioles 4

Moneyline

The GUARDIANS (-105) are worth a look as short ‘dogs in this clash of potential American League playoff teams.

Bibee has emerged as a solid option in the Cleveland rotation, and he tends to do his best work on the road.

While Povich has done a decent job against the Braves and Yankees in his fledgling career, it’s a tough matchup against a red-hot Guards offense.

Run line/Against the spread

The Orioles +1.5 (-190) will cost you nearly 2 times your potential return, if you can’t bring yourself to back Baltimore straight up and need a little bit of insurance.

If you like the O’s, just bet them straight up.

AVOID.

Over/Under

OVER 8.5 (-105) is the lean, but only roll with a half-unit play at most.

The Over is on a 6-2-1 run in the past 9 games for the Orioles, including 2-0-1 in the past 3 appearances at home.

The Guardians split the total 1-1-1 in the 3-game sweep of the Blue Jays this past weekend, but the Over is on a 5-1-1 run in the previous 7 outings dating back to June 16.

Play our free daily Pick’em Challenge and win! Play now!

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Fantasy baseball help from BaseballHQ.com:
Subscribe now to dominate the competition.