The Boston Red Sox (5-2) and Los Angeles Angels (4-2) open a 3-game series Friday. First pitch from Angel Stadium is slated for 9:38 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Red Sox vs. Angels odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Angels won 4-3 last season

The Red Sox are in the midst of a 10-game road trip to start the 2024 season. After splitting 4 games against the Seattle mariners, Boston just completed a sweep of the Oakland Athletics, holding them to a grand total of 4 runs over the 3 games. Boston’s pitching staff has a 1.54 ERA through 7 games. The Red Sox will play their 1st game at Fenway Park on Tuesday against the Baltimore Orioles.

The Angels just wrapped up a 6-game road trip with a 3-game sweep of the Marlins in Miami. After allowing 24 runs in their 1st 2 games, the Angels have given up just 8 during a current 4-game win streak. The Halos have been carried offensively by red-hot LF Taylor Ward, batting .320 with 3 HRs and 8 RBI.

Red Sox at Angels projected starters

RHP Kutter Crawford vs. RHP Griffin Canning

Crawford (0-0, 0.00 ERA) makes his 2nd start. He has a 0.67 WHIP, 1.5 BB/9 and 10.5 K/9 in 6 innings.

  • 2023 road stats: 6-3, 2.49 ERA (72 1/3 IP, 20 ER) in 12 starts and 4 relief appearances
  • Last start vs. Mariners: No-decision, 6 IP, 0 ER, 3 H, 1 BB, 7 K in a 4-3 road loss Saturday
  • Has never faced the Angels as a starter

Canning (0-1, 9.00 ERA) makes his 2nd start. He has a 1.60 WHIP, 1.8 BB/9 and 3.6 K/9 in 5 innings.

  • 2023 home stats: 4-5, 4.66 ERA (58 IP, 30 ER) in 10 starts and 1 relief appearances
  • Last start vs. Orioles: Loss, 5 IP, 5 ER, 7 H, 1 BB, 2 K in a 13-4 road loss Saturday
  • Last start vs. Red Sox: Win, 7 IP, 0 ER, 2 H, 3 BB, 5 K in a 4-0 home loss on May 23, 2023

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Red Sox at Angels odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:23 a.m. ET.

  • Moneyline (ML): Red Sox -105 (bet $105 to win $100) | Angels -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Red Sox -1.5 (+155) | Angels +1.5 (-190)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

Red Sox at Angels picks and predictions

Prediction

Red Sox 4, Angels 2

Moneyline

BET RED SOX (-105).

While both teams come into this series red hot, I like Boston to take the opener on Friday night.

Crawford looked great in his 1st start against the Mariners. Canning got knocked around for 5 ER by the Orioles in his 2024 debut. Griffin has just 1 victory since Aug. 1, 2023 (over 9 starts).

The Angels are hitting just .202  as a team against righties with a 2-2 record. Boston is 4-2 against righties hitting .250 as a team.

Run line/Against the spread

PASS.

I’m going to save my bet for the moneyline, and not pay that juice on the spread.

Over/Under

AVOID.

My lean is the Under as you can tell from my Game prediction, but I’m not confident enough to make it my official bet. These 2 teams are 9-11 against the Over in their last 20 Games combined. I just don’t see an edge in either direction, I’d rather save my wager for the moneyline.

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