Our computer prediction calls for a relatively tight win (24-21) for the Buffalo Bills (8-2) over the Kansas City Chiefs (9-0) on Sunday, Nov. 17 at Highmark Stadium (kickoff at 4:25 p.m. ET).

Bills vs. Chiefs predictions

  • Pick ATS: Bills (-2.5)
  • Pick OU: Under (46.5)
  • Prediction:
    Bills 24 – Chiefs 21

Bills vs. Chiefs odds and lines

National Football League odds courtesy of BetMGM. Odds updated Sunday at 1:34 p.m. ET. For a full list of Sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Spread favorite: Bills (-2.5)
  • Moneyline: Bills (-140), Chiefs (+120)
  • Total: 46.5 points

Bills betting stats

  • Buffalo has six wins in 10 games against the spread this season.
  • The Bills are 4-2 as 2.5-point favorites or more.
  • Buffalo has played 10 games this year, and six of them have hit the over.

Chiefs betting stats

  • Kansas City is 4-4-1 against the spread this year.
  • The Chiefs are yet to lose ATS (1-0) as a 2.5-point underdog or greater this season.
  • Of nine Kansas City games so far this year, four have gone over the total.
  • The Chiefs won the only game they’ve played as the underdog this season.

Bills vs. Chiefs game info

  • Game day: Sunday, November 17, 2024
  • Game time: 4:25 p.m. ET
  • TV channel: CBS
  • Location: Orchard Park, New York
  • Stadium: Highmark Stadium
  • TV channel: CBS
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  • Live stream: Watch on Paramount+!
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