The Week 6 NFL schedule has plenty of quality competition on the docket. Among those contests is the Tampa Bay Buccaneers squaring off against the New Orleans Saints.
Check out our odds breakdown for the NFL’s Week 6.
Week 6 NFL games: betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 3:38 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Thursday
San Francisco 49ers at Seattle Seahawks odds and lines
The San Francisco 49ers will match up with the Seattle Seahawks at 8:15 p.m. ET on Thursday at Lumen Field in Seattle, Washington.
- Favorite: 49ers (-3.5)
- Total: 49.5
- Moneyline: 49ers (-187) | Seahawks (+157)
- Live Stream: Watch on Prime Video
Click here for a full betting preview
Sunday
Jacksonville Jaguars at Chicago Bears odds and lines
The Jacksonville Jaguars will square off against the Chicago Bears at 9:30 a.m. ET on Sunday at Tottenham Hotspur Stadium in London, England.
- Favorite: Bears (-2)
- Total: 44.5
- Moneyline: Bears (-132) | Jaguars (+111)
- Live Stream: Watch on Fubo
Cleveland Browns at Philadelphia Eagles odds and lines
The Cleveland Browns will square off against the Philadelphia Eagles at 1:00 p.m. ET on Sunday at Lincoln Financial Field in Philadelphia, Pennsylvania.
- Favorite: Eagles (-9.5)
- Total: 42.5
- Moneyline: Eagles (-457) | Browns (+353)
- Live Stream: Watch on Fubo
Houston Texans at New England Patriots odds and lines
The Houston Texans take on the New England Patriots at 1:00 p.m. ET on Sunday at Gillette Stadium in Foxborough, Massachusetts.
- Favorite: Texans (-7)
- Total: 38
- Moneyline: Texans (-328) | Patriots (+258)
- Live Stream: Watch on Fubo
Tampa Bay Buccaneers at New Orleans Saints odds and lines
The Tampa Bay Buccaneers hit the field against the New Orleans Saints at 1:00 p.m. ET on Sunday at Caesars Superdome in New Orleans, Louisiana.
- Favorite: Buccaneers (-3.5)
- Total: 41.5
- Moneyline: Buccaneers (-184) | Saints (+153)
- Live Stream: Watch on Fubo
Arizona Cardinals at Green Bay Packers odds and lines
The Arizona Cardinals match up with the Green Bay Packers at 1:00 p.m. ET on Sunday at Lambeau Field in Green Bay, Wisconsin.
- Favorite: Packers (-5.5)
- Total: 47.5
- Moneyline: Packers (-242) | Cardinals (+197)
- Live Stream: Watch on Fubo
Washington Commanders at Baltimore Ravens odds and lines
The Washington Commanders play the Baltimore Ravens at 1:00 p.m. ET on Sunday at M&T Bank Stadium in Baltimore, Maryland.
- Favorite: Ravens (-6.5)
- Total: 51.5
- Moneyline: Ravens (-292) | Commanders (+237)
- Live Stream: Watch on Fubo
Indianapolis Colts at Tennessee Titans odds and lines
The Indianapolis Colts match up with the Tennessee Titans at 1:00 p.m. ET on Sunday at Nissan Stadium in Nashville, Tennessee.
- Favorite: Titans (-2.5)
- Total: 43
- Moneyline: Titans (-133) | Colts (+112)
- Live Stream: Watch on Fubo
Pittsburgh Steelers at Las Vegas Raiders odds and lines
The Pittsburgh Steelers meet the Las Vegas Raiders at 4:05 p.m. ET on Sunday at Allegiant Stadium in Paradise, Nevada.
- Favorite: Steelers (-3)
- Total: 36.5
- Moneyline: Steelers (-166) | Raiders (+140)
- Live Stream: Watch on Fubo
Los Angeles Chargers at Denver Broncos odds and lines
The Los Angeles Chargers match up with the Denver Broncos at 4:05 p.m. ET on Sunday at Empower Field at Mile High in Denver, Colorado.
- Favorite: Chargers (-3)
- Total: 35.5
- Moneyline: Chargers (-153) | Broncos (+129)
- Live Stream: Watch on Fubo
Detroit Lions at Dallas Cowboys odds and lines
The Detroit Lions will take the field against the Dallas Cowboys at 4:25 p.m. ET on Sunday at AT&T Stadium in Arlington, Texas.
- Favorite: Lions (-3)
- Total: 52
- Moneyline: Lions (-164) | Cowboys (+138)
- Live Stream: Watch on Fubo
Atlanta Falcons at Carolina Panthers odds and lines
The Atlanta Falcons square off against the Carolina Panthers at 4:25 p.m. ET on Sunday at Bank of America Stadium in Charlotte, North Carolina.
- Favorite: Falcons (-6)
- Total: 47
- Moneyline: Falcons (-263) | Panthers (+214)
- Live Stream: Watch on Fubo
Cincinnati Bengals at New York Giants odds and lines
The Cincinnati Bengals will square off against the New York Giants at 8:20 p.m. ET on Sunday at MetLife Stadium in East Rutherford, New Jersey.
- Favorite: Bengals (-3.5)
- Total: 48
- Moneyline: Bengals (-176) | Giants (+146)
- Live Stream: Watch on Fubo
- Live Stream: Watch on Peacock
Monday
Buffalo Bills at New York Jets odds and lines
The Buffalo Bills will take on the New York Jets at 8:15 p.m. ET on Monday at MetLife Stadium in East Rutherford, New Jersey.
- Favorite: Bills (-2.5)
- Total: 41
- Moneyline: Bills (-140) | Jets (+118)
- Live Stream: Watch on Fubo
