The New Orleans Saints going head to head against the Kansas City Chiefs is one of many solid options on the Week 5 NFL schedule.
Here is the betting info to break down ahead of Week 5 in the NFL.
Watch the NFL on Fubo!NFL Week 5 betting odds and lines
NFL odds courtesy of BetMGM UHd4ZsH01H3QKBOok. Odds updated Tuesday at 9:06 p.m. ET. For a full list of Sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Thursday
Tampa Bay Buccaneers at Atlanta Falcons betting odds
- Game time: 8:15 p.m. ET on Thursday, Oct. 3
- Game location: Mercedes-Benz Stadium in Atlanta, Georgia
- Spread favorite: Falcons (-1.5)
- Over/under: 43.5 points
- Moneyline odds: Falcons (-126) | Buccaneers (+106)
- TV channel: Amazon Prime Video
- Live stream: Watch on Prime Video
Click here for a full betting preview
Sunday
New York Jets at Minnesota Vikings betting odds
- Game time: 9:30 a.m. ET on Sunday, Oct. 6
- Game location: Tottenham Hotspur Stadium in London, England
- Spread favorite: Vikings (-2.5)
- Over/under: 40.5 points
- Moneyline odds: Vikings (-151) | Jets (+127)
- TV channel: NFL Network
- Live stream: Watch on Fubo
Buffalo Bills at Houston Texans betting odds
- Game time: 1:00 p.m. ET on Sunday, Oct. 6
- Game location: NRG Stadium in Houston, Texas
- Spread favorite: Bills (-1)
- Over/under: 47.5 points
- Moneyline odds: Bills (-118) | Texans (-101)
- TV channel: CBS
- Live stream: Fubo | Paramount+
Carolina Panthers at Chicago Bears betting odds
- Game time: 1:00 p.m. ET on Sunday, Oct. 6
- Game location: Soldier Field in Chicago, Illinois
- Spread favorite: Bears (-4)
- Over/under: 42 points
- Moneyline odds: Bears (-194) | Panthers (+162)
- TV channel: FOX
- Live stream: Watch on Fubo
Baltimore Ravens at Cincinnati Bengals betting odds
- Game time: 1:00 p.m. ET on Sunday, Oct. 6
- Game location: Paycor Stadium in Cincinnati, Ohio
- Spread favorite: Ravens (-2.5)
- Over/under: 50.5 points
- Moneyline odds: Ravens (-147) | Bengals (+124)
- TV channel: CBS
- Live stream: Fubo | Paramount+
Miami Dolphins at New England Patriots betting odds
- Game time: 1:00 p.m. ET on Sunday, Oct. 6
- Game location: Gillette Stadium in Foxborough, Massachusetts
- Spread favorite: Patriots (-1)
- Over/under: 35.5 points
- Moneyline odds: Patriots (-116) | Dolphins (-104)
- TV channel: FOX
- Live stream: Watch on Fubo
Indianapolis Colts at Jacksonville Jaguars betting odds
- Game time: 1:00 p.m. ET on Sunday, Oct. 6
- Game location: EverBank Stadium in Jacksonville, Florida
- Spread favorite: Jaguars (-3)
- Over/under: 46.5 points
- Moneyline odds: Jaguars (-149) | Colts (+126)
- TV channel: CBS
- Live stream: Fubo | Paramount+
Cleveland Browns at Washington Commanders betting odds
- Game time: 1:00 p.m. ET on Sunday, Oct. 6
- Game location: Commanders Field in Landover, Maryland
- Spread favorite: Commanders (-3.5)
- Over/under: 44.5 points
- Moneyline odds: Commanders (-173) | Browns (+145)
- TV channel: FOX
- Live stream: Watch on Fubo
Arizona Cardinals at San Francisco 49ers betting odds
- Game time: 4:05 p.m. ET on Sunday, Oct. 6
- Game location: Levi’s Stadium in Santa Clara, California
- Spread favorite: 49ers (-7.5)
- Over/under: 49.5 points
- Moneyline odds: 49ers (-357) | Cardinals (+281)
- TV channel: FOX
- Live stream: Watch on Fubo
Las Vegas Raiders at Denver Broncos betting odds
- Game time: 4:05 p.m. ET on Sunday, Oct. 6
- Game location: Empower Field at Mile High in Denver, Colorado
- Spread favorite: Broncos (-3)
- Over/under: 36 points
- Moneyline odds: Broncos (-150) | Raiders (+127)
- TV channel: FOX
- Live stream: Watch on Fubo
Green Bay Packers at Los Angeles Rams betting odds
- Game time: 4:25 p.m. ET on Sunday, Oct. 6
- Game location: SoFi Stadium in Inglewood, California
- Spread favorite: Packers (-3.5)
- Over/under: 47.5 points
- Moneyline odds: Packers (-179) | Rams (+149)
- TV channel: CBS
- Live stream: Fubo | Paramount+
New York Giants at Seattle Seahawks betting odds
- Game time: 4:25 p.m. ET on Sunday, Oct. 6
- Game location: Lumen Field in Seattle, Washington
- Spread favorite: Seahawks (-6)
- Over/under: 43.5 points
- Moneyline odds: Seahawks (-273) | Giants (+220)
- TV channel: CBS
- Live stream: Fubo | Paramount+
Dallas Cowboys at Pittsburgh Steelers betting odds
- Game time: 8:20 p.m. ET on Sunday, Oct. 6
- Game location: Acrisure Stadium in Pittsburgh, Pennsylvania
- Spread favorite: Steelers (-2.5)
- Over/under: 43 points
- Moneyline odds: Steelers (-138) | Cowboys (+117)
- TV channel: NBC
- Live stream: Fubo | Peacock
Monday
New Orleans Saints at Kansas City Chiefs betting odds
- Game time: 8:15 p.m. ET on Monday, Oct. 7
- Game location: GEHA Field at Arrowhead Stadium in Kansas City, Missouri
- Spread favorite: Chiefs (-5)
- Over/under: 42.5 points
- Moneyline odds: Chiefs (-228) | Saints (+188)
- TV channel: ESPN
- Live stream: Watch on Fubo
