The Chicago White Sox (18-53) play the 2nd game of their 3-game series against the Arizona Diamondbacks (34-36) Saturday. First pitch from Chase Field is scheduled for 10:10 p.m. ET (FS1). Let’s analyze BetMGM Sportsbook’s lines around the White Sox vs. Diamondbacks odds and make our expert MLB picks and predictions for the best bets.

Season series: Diamondbacks lead 1-0

The White Sox are 1-4 on their current 7-game road trip and 1-5 in their last 6 games overall, including a 7-1 defeat to Arizona in the series opener Friday.

The Diamondbacks got a career-high 8 K’s from starter RHP Ryne Nelson over 8 innings in the win Friday. It was their 2nd straight win and 4th in 5 games. They are 8-4 in their last 12.

White Sox at Diamondbacks projected starters

RHP Erick Fedde vs. RHP Scott McGough

Fedde (4-1, 3.10 ERA) makes his 15th start. He has a 1.16 WHIP, 2.5 BB/9 and 8.5 K/9 in 81 1/3 IP.

  • Last start: No-decision, 7 IP, 1 R, 5 H, 1 BB, 4 K in 8-4 road loss to Seattle Mariners Monday
  • White Sox have lost his last 5 starts

McGough (1-3, 5.85 ERA) is the opener for Arizona for the 2nd time this season in his 19th appearance. He has a 1.70 WHIP, 5.4 BB/9 and 6.3 K/9 in 20 IP.

  • Last start: No-decision, 2/3 IP, 1 ER, 1 H, 0 BB, 1 K in 9-3 win at San Diego Padres Sunday
  • 2024 home stats: 1-1, 3.29 ERA (13 2/3 IP, 5 ER), 1.46 WHIP, 7.2 K/9 in 11 relief appearances

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

White Sox at Diamondbacks odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:35 a.m. ET.

  • Moneyline (ML): White Sox +135 (bet $100 to win $135) | Diamondbacks -160 (bet $160 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-145) | Diamondbacks -1.5 (+120)
  • Over/Under (O/U): 9 (O: +100 | U: -120)

White Sox at Diamondbacks picks and predictions

Prediction

Diamondbacks 7, White Sox 3

Moneyline

Chicago is 6-30 on the road this season, the worst mark in all of baseball. They have only 1 win in their last 11 road games.

The Diamondbacks, although only 18-17 at home this season, have taken care of lesser competition with a 22-17 record against teams who do not have winning records. Their offense has come alive, scoring 7 or more in 4 of their last 5 games.

But at -160 odds, betting them on the moneyline isn’t the value you want.

PASS.

Run line/Against the spread

Ten of the Diamondbacks’ last 13 wins have been by 2 or more runs.

The White Sox are 31-40 ATS overall this season and a league-worst 14-22 ATS on the road.

BET DIAMONDBACKS -1.5 (+120).

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Over/Under

Friday’s Game had only 8 total runs, but the Diamondbacks had 6 straight Games and 8 of 9 before that with 10 or more runs.

They have scored 7 or more themselves in 4 straight wins and in 5 of their last 6 victories.

BET OVER 9 (+100).

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