The Los Angeles Chargers (2-1) will meet the Kansas City Chiefs (3-0) at SoFi Stadium on Sunday, Sept. 29 at 4:25 p.m. ET, and our computer prediction is a narrow win by the Chargers, 20-18.

Chiefs vs. Chargers predictions

  • Pick ATS: Chargers (+7)
  • Pick OU: Under (41.5)
  • Prediction:
    Chargers 20 – Chiefs 18

Chiefs vs. Chargers odds and lines

National Football League odds courtesy of BetMGM. Odds updated Sunday at 1:35 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Spread favorite: Chiefs (-7)
  • Moneyline: Chiefs (-350), Chargers (+280)
  • Total: 41.5 points

Chiefs betting stats

  • Kansas City has won twice against the spread this season.
  • Kansas City has had two games (out of three) go over the total this season.

Chargers betting stats

  • Los Angeles has won twice against the spread this year.
  • None of Los Angeles’ three games has hit the over in 2024.
  • The Chargers lost the only game they’ve played as the underdog this season.

Chiefs vs. Chargers game info

  • Game day: Sunday, September 29, 2024
  • Game time: 4:25 p.m. ET
  • TV channel: CBS
  • Location: Inglewood, California
  • Stadium: SoFi Stadium
  • TV channel: CBS
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